3-(6-bromo-1H-indol-3-yl)propanoic Acid

Base Information

Chemical Name:3-(6-bromo-1H-indol-3-yl)propanoic Acid
CAS No.:210569-69-0
Molecular Formula:C₁₁H₁₀BrNO₂
Molecular Weight:268.11
Hs Code.:
DSSTox Substance ID:DTXSID10446551
Mol file:210569-69-0.mol

Synonyms:210569-69-0;3-(6-bromo-1H-indol-3-yl)propanoic Acid;3-(6-Bromo-3-indolyl)propanoic Acid;MFCD10035286;1H-Indole-3-propanoic acid, 6-bromo-;BENZYL4-TOLUENESULFONATE;DTXSID10446551;AC8138;AS-78458;SY250572

Suppliers and Price of 3-(6-bromo-1H-indol-3-yl)propanoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-(6-bromo-1H-indol-3-yl)propanoicacid 95
25g
$ 2200.00

American Custom Chemicals Corporation
3-(6-BROMO-1H-INDOL-3-YL)PROPANOIC ACID 95.00%
5MG
$ 497.70

Aaron Chemicals
1H-Indole-3-propanoicacid,6-bromo- 90%
100mg
$ 292.00

Total 2 raw suppliers

Chemical Property of 3-(6-bromo-1H-indol-3-yl)propanoic Acid

Chemical Property:

PSA：53.09000
LogP:2.94760
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:266.98949
Heavy Atom Count:15
Complexity:247

Purity/Quality:

99% ^*data from raw suppliers

3-(6-bromo-1H-indol-3-yl)propanoicacid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1Br)NC=C2CCC(=O)O

Technology Process of 3-(6-bromo-1H-indol-3-yl)propanoic Acid

There total 5 articles about 3-(6-bromo-1H-indol-3-yl)propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 210889-33-1
3-(6-bromo-3H-indol-3-yl)-propionic acid methyl ester

: 210569-69-0
3-(6-bromo-3H-indol-3-yl)-propionic acid

Guidance literature:: With sodium hydroxide; In methanol; for 4h; Ambient temperature;
DOI:10.1016/S0040-4020(99)00171-4

Reference yield:

: 52415-29-9
6-bromo-1H-indole

: 79-10-7
acrylic acid

: 210569-69-0
3-(6-bromo-3H-indol-3-yl)-propionic acid

Guidance literature:: With acetic anhydride; In acetic acid; at 95 ℃;
DOI:10.1021/acs.joc.1c01313

Reference yield:

: 17826-04-9
6-bromo-1H-indole-3-carbaldehyde

: 210569-69-0
3-(6-bromo-3H-indol-3-yl)-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / piperidine / pyridine / 24 h / 50 °C

2: 75 percent / BiCl₃, NaBH₄ / aq. ethanol / 24 h / 0 °C

3: 94 percent / aq. NaOH / methanol / 4 h / Ambient temperature

With piperidine; bismuth(III) chloride; sodium hydroxide; sodium tetrahydroborate; In pyridine; methanol; ethanol;
DOI:10.1016/S0040-4020(99)00171-4