4,6-DICHLORO-2-PHENYLQUINOLINE

Base Information

• Chemical Name: 4,6-DICHLORO-2-PHENYLQUINOLINE
• CAS No.: 100914-76-9
• Molecular Formula: C15H9Cl2N
• Molecular Weight: 274.149
• Mol file: 100914-76-9.mol

Synonyms:4,6-DICHLORO-2-PHENYLQUINOLINE

Chemical Property of 4,6-DICHLORO-2-PHENYLQUINOLINE

Chemical Property:

• Vapor Pressure: 3.11E-06mmHg at 25°C
• Boiling Point: 399.6°C at 760 mmHg
• Flash Point: 227.8°C
• PSA: 12.89000
• Density: 1.331g/cm³
• LogP: 5.20860

Purity/Quality:

98%min ^*data from raw suppliers

4,6-DICHLORO-2-PHENYLQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,6-DICHLORO-2-PHENYLQUINOLINE

There total 5 articles about 4,6-DICHLORO-2-PHENYLQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-chloro-2-phenyl-quinolin-4-ol (17282-72-3) → 4,6-dichloro-2-phenylquinoline (100914-76-9)

Guidance literature:

With trichlorophosphate;

Reference yield:

ethyl 3-oxo-3-phenylpropionate (94-02-0) → 4,6-dichloro-2-phenylquinoline (100914-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: water; hydrochloric acid / und Behandeln des Reaktionsprodukts mit konz. Schwefelsaeure und Acetanhydrid

2: phosphoryl chloride

With hydrogenchloride; water; trichlorophosphate;

Reference yield:

4-chloro-aniline (106-47-8) → 4,6-dichloro-2-phenylquinoline (100914-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: water; hydrochloric acid / und Behandeln des Reaktionsprodukts mit konz. Schwefelsaeure und Acetanhydrid

2: phosphoryl chloride

With hydrogenchloride; water; trichlorophosphate;

upstream raw materials:

6-chloro-2-phenyl-quinolin-4-ol

ethyl 3-oxo-3-phenylpropionate

4-chloro-aniline

Refernces

• 1、 Huang, Guang,Murillo Solano, Claribel,Melendez, Joel,Shaw, Justin,Collins, Jennifer,Banks, Robert,Arshadi, Arash Keshavarzi,Boonhok, Rachasak,Min, Hui,Miao, Jun,Chakrabarti, Debopam,Yuan, Yu. "Synthesis, Structure-Activity Relationship, and Antimalarial Efficacy of 6-Chloro-2-arylvinylquinolines". . p. 11756 - 11785. Retrieved 2020/11/26.
• 2、 -. "4-Piperidino-2-phenylquinolines". . . Retrieved 2008/06/13.