17282-72-3

Basic information

• Product Name: 6-CHLORO-4-HYDROXY-2-PHENYLQUINOLINE
• Synonyms: OTAVA-BB BB7018670039;6-CHLORO-4-HYDROXY-2-PHENYLQUINOLINE;6-Chloro-2-phenyl-4-quinolinol;6-Chloro-2-phenylquinolin-4-ol
• CAS NO: 17282-72-3
• Molecular Formula: C₁₅H₁₀ClNO
• Molecular Weight: 255.7
• Mol File: 17282-72-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 421.8°Cat760mmHg
• Flash Point: 208.9°C
• Appearance: /
• Density: 1.303g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-CHLORO-4-HYDROXY-2-PHENYLQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-4-HYDROXY-2-PHENYLQUINOLINE(17282-72-3)
• EPA Substance Registry System: 6-CHLORO-4-HYDROXY-2-PHENYLQUINOLINE(17282-72-3)

Safety Data

• Hazardous Substances Data: 17282-72-3(Hazardous Substances Data)

Usage

General Description

6-Chloro-4-hydroxy-2-phenylquinoline is a chemical compound with the molecular formula C16H10ClNO. It is a quinoline derivative that contains a chlorine atom and a hydroxy group attached to the quinoline ring, as well as a phenyl group. 6-CHLORO-4-HYDROXY-2-PHENYLQUINOLINE is used in medicinal chemistry for its potential pharmaceutical properties and has been investigated for its potential as an anti-infective and antimicrobial agent. It may also have applications in the field of organic synthesis and chemical research as a building block for the synthesis of other compounds. Additionally, it may have potential as a fluorescent probe or dye due to its quinoline structure. Overall, 6-Chloro-4-hydroxy-2-phenylquinoline has garnered interest for its potential biological and chemical applications and continues to be the subject of scientific study and investigation.

Upstream product

• 100-00-5 4-chlorobenzonitrile 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 106-47-8 4-chloro-aniline 
• 93663-74-2 ethyl 6-chloro-4-hydroxy-2-phenylquinoline-3-carboxylate 
• 204913-35-9 6-Chloro-2-phenyl-4-(toluene-4-sulfonyl)-quinoline 

Downstream Products

• 100914-76-9 4,6-dichloro-2-phenylquinoline 

Relevant articles and documents

ANTIMALARIAL COMPOUNDS

Antimalarial compounds of the formula: in which n is 1 or 2; X is C or N; R1 is a moiety comprising a secondary amine and a tertiary amine joined by a C2 to C4 alkyl chain; and R2 is CF3, F, or H, or an analog, combination, derivative, prodrug, stereoisomer, or pharmaceutically acceptable salt thereof. Pharmaceutical compounds including the antimalarial compounds. Methods of treating or preventing malaria comprising administering an effective amount of the antimalarial compounds.

Silane-mediated direct condensation of nitroarenes with cinnamyl-type sulfones. The way to 2-aryl-4-X-quinolines and their hetero analogs

DBU/silane mediated double condensation of nitroarenes with cinnamyl-type sulfones proceeds smoothly to yield 2-arl-4-arylsulfonyl quinolines and their hetero analogs. Arylsulfonyl group can be easily replaced by different nucleophiles.

4-Piperidino-2-phenylquinolines

Disclosed are compounds of the formula STR1 wherein: R1 and R2 may be either the same or different and each is hydrogen or lower alkyl; and wherein R3 and R4 may be either the same or different and each is hydrogen, halogen, or lower alkyl, with the proviso that R3 and R4 cannot both be hydrogen. These compounds are useful as anticonvulsant or anxiolytic agents.