3-bromoquinolin-6-yl acetate

Base Information

• Chemical Name: 3-bromoquinolin-6-yl acetate
• CAS No.: 1022151-47-8
• Molecular Formula: C11H8BrNO2
• Molecular Weight: 266
• Hs Code.: 2933499090
• Mol file: 1022151-47-8.mol

Synonyms:3-bromoquinolin-6-yl acetate;6-Acetoxy-3-bromoquinoline;6-Acetoxy-3-bromoquinoline, Acetic acid 3-bromoquinolin-6-yl ester;6-Quinolinol, 3-bromo-, 6-acetate

Chemical Property of 3-bromoquinolin-6-yl acetate

Chemical Property:

• PSA: 39.19000
• LogP: 2.92260
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-Bromoquinolin-6-ylacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-bromoquinolin-6-yl acetate

There total 2 articles about 3-bromoquinolin-6-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

methyl quinolin-6-ylethanoate (24306-33-0) → 3-bromoquinolin-6-yl acetate (1022151-47-8)

Guidance literature:

With pyridine; bromine; In 1,1,2,2-tetrachloroethane; at 0 - 90 ℃; for 3h; Inert atmosphere;

Reference yield:

6-hydroxyquinoline (580-16-5) → 3-bromoquinolin-6-yl acetate (1022151-47-8)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 8 h / 0 - 20 °C

2: bromine; pyridine / tetrachloromethane / 3 h / 0 - 90 °C

With pyridine; bromine; In tetrachloromethane; dichloromethane;

Reference yield: 86.0%

3-bromoquinolin-6-yl acetate (1022151-47-8) → 3-bromo-6-hydroxyquinoline (13669-57-3)

Guidance literature:

With methanol; potassium carbonate; In water monomer; at 20 ℃; for 2h;

upstream raw materials:

methyl quinolin-6-ylethanoate

6-hydroxyquinoline

Downstream raw materials:

3-bromo-6-hydroxyquinoline

6-(benzyloxy)-3-bromoquinoline

(S)-1-(6-(benzyloxy)quinolin-3-yl)-N,N-dimethylpyrrolidin-3-amine

N-((6-(benzyloxy)quinolin-3-yl)methyl)-N-ethylethanamine