24306-33-0

Basic information

• Product Name: quinolin-6-yl acetate
• Synonyms: quinolin-6-yl acetate;6-acetoxy-quinoline
• CAS NO: 24306-33-0
• Molecular Formula: C₁₁H₉NO₂
• Molecular Weight: 187
• Mol File: 24306-33-0.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: quinolin-6-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: quinolin-6-yl acetate(24306-33-0)
• EPA Substance Registry System: quinolin-6-yl acetate(24306-33-0)

Safety Data

• Hazardous Substances Data: 24306-33-0(Hazardous Substances Data)

Usage

General Description

Quinolin-6-yl acetate is a chemical compound that is classified as an acetate ester derivative of quinoline. It falls into the category of organic compounds known as quinolines and derivatives, which are compounds containing a quinoline moiety, a structure made up of two fused rings, a benzene ring and a pyridine ring sharing two neighboring carbon atoms. The molecular formula of quinolin-6-yl acetate is C11H9NO2 and its mass is 187.194 g/mol. This chemical has a wide range of applications in different industries including the pharmaceutical industry. However, data regarding its toxicity and safety profile is limited, but it should be handled carefully due to its potentially reactive nature.

Upstream product

• 123-30-8 4-amino-phenol 
• 580-16-5 6-hydroxyquinoline 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 889660-68-8 3-iodo-6-hydroxyquinoline 
• 14036-96-5 3-bromo-6-methoxyquinoline 
• 1393352-93-6 N-((6-(benzyloxy)quinolin-3-yl)methyl)-N-ethylethanamine 
• 1393352-90-3 (S)-1-(6-(benzyloxy)quinolin-3-yl)-N,N-dimethylpyrrolidin-3-amine 
• 1337882-50-4 6-(benzyloxy)-3-bromoquinoline 
• 13669-57-3 3-bromo-6-hydroxyquinoline 
• 1022151-47-8 3-bromoquinolin-6-yl acetate 
• 855871-82-8 6-acetoxy-1-benzoyl-1,2,3,4-tetrahydro-quinoline 
• 873970-10-6 1-cyclohexanecarbonyl-1,2,3,4-tetrahydro-quinolin-6-ol 
• 1427474-57-4 4-(6-(benzyloxy)quinolin-3-yl)-3-methylmorpholine 
• 727650-61-5 3-aminoquinolin-6-ol 
• 1427474-53-0 N-benzyl-6-(benzyloxy)quinolin-3-amine 
• 1427474-50-7 6-(benzyloxy)-N-(2-(tert-butyldimethylsilyloxy)ethyl)quinolin-3-amine 
• 1427473-97-9 6-(benzyloxy)-3-(4-methyl-1,4-diazepan-1-yl)quinoline 

Relevant articles and documents

-

-

2'-(QUINOLIN-3-YL)-5',6'-DIHYDROSPIRO[AZETIDINE-3,4'-PYRROLO[1,2-B]PYRAZOLE]-1-CARBOXYLATE DERIVATIVES AND RELATED COMPOUNDS AS MAP4K1 (HPK1) INHIBITORS FOR THE TREATMENT OF CANCER

The present invention relates to Map4K1 inhibitors of formula (I), to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients. The present invention further relates to the use, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of protein inhibitors in benign hyperplasias, atherosclerotic disorders, sepsis, autoimmune disorders, vascular disorders, viral infections, in neurodegenerative disorders, in inflammatory disorders, in atherosclerotic disorders and in male fertility control.

ALK5 INHIBITORS

The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.