N,N',N''-Tri-Boc-guanidine

Base Information

Chemical Name:N,N',N''-Tri-Boc-guanidine
CAS No.:216584-22-4
Molecular Formula:C16H29N3O6
Molecular Weight:359.423
Hs Code.:
European Community (EC) Number:693-309-0
DSSTox Substance ID:DTXSID20441916
Nikkaji Number:J1.066.316D
Mol file:216584-22-4.mol

Synonyms:N,N',N''-Tri-Boc-guanidine;216584-22-4;1,2,3-Tris(tert-butoxycarbonyl)guanidine;tert-butyl N-[bis[(2-methylpropan-2-yl)oxycarbonylamino]methylidene]carbamate;SCHEMBL3144118;N-,N'-,N"-Tri-Boc-guanidine;DTXSID20441916;XZGNHTJSFCBWHG-UHFFFAOYSA-N;N-,N'-,N''-Tri-Boc-Guanidine;MFCD11656061;N,N',N''-Tri-Boc-guanidine, 97%;AS-30325;N,N inverted exclamation marka,N inverted exclamation marka inverted exclamation marka-Tri-Boc-guanidine;CS-0173626;T2964;A935402;J-014212

Suppliers and Price of N,N',N''-Tri-Boc-guanidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
N,N′,N′′-Tri-Boc-guanidine 97%
5g
$ 129.00

Chem-Impex
N,N,N-Tri-Boc-guanidine,98%(Assaybytitration) 98%(Assaybytitration)
5G
$ 106.40

Chem-Impex
N,N,N-Tri-Boc-guanidine,≥98%(Assaybytitration) ≥98%(Assaybytitration)
1G
$ 52.42

Chem-Impex
N,N,N-Tri-Boc-guanidine,98%(Assaybytitration) 98%(Assaybytitration)
250MG
$ 28.00

Chem-Impex
N,N,N-Tri-Boc-guanidine,98%(Assaybytitration) 98%(Assaybytitration)
25G
$ 498.40

American Custom Chemicals Corporation
N,N',N''-TRI-BOC-GUANIDINE 97.00%
5G
$ 898.29

American Custom Chemicals Corporation
N,N',N''-TRI-BOC-GUANIDINE 97.00%
1G
$ 283.50

AK Scientific
N,N′,N′′-Tri-Boc-guanidine
5g
$ 190.00

Total 9 raw suppliers

Chemical Property of N,N',N''-Tri-Boc-guanidine

Chemical Property:

Melting Point:190-196 °C
PKA:5.88±0.46(Predicted)
PSA：122.30000
Density:1.10±0.1 g/cm3(Predicted)
LogP:3.73570
Storage Temp.:2-8°C
XLogP3:4.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:359.20563565
Heavy Atom Count:25
Complexity:504

Purity/Quality:

99% ^*data from raw suppliers

N,N′,N′′-Tri-Boc-guanidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C

Technology Process of N,N',N''-Tri-Boc-guanidine

There total 3 articles about N,N',N''-Tri-Boc-guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 50-01-1
guanidine hydrochloride

: 332882-82-3,154476-57-0
1,3-bis(t-butoxycarbonyl)guanidine

: 216584-22-4
N¹,N²,N³-tris(tert-butoxycarbonyl)guanidine

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; at 0 - 20 ℃; for 26h;
DOI:10.1055/s-2004-829130

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 50-01-1
guanidine hydrochloride

: 332882-82-3,154476-57-0
1,3-bis(t-butoxycarbonyl)guanidine

: 219511-71-4
tert-butyl carbamimidoylcarbamate

: 216584-22-4
N¹,N²,N³-tris(tert-butoxycarbonyl)guanidine

Guidance literature:: With sodium hydroxide; Yield given; Multistep reaction; 1.) dioxane, water, 2.) dioxane, water, room temperature;
DOI:10.1021/jo9814344

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 50-01-1
guanidine hydrochloride

: 216584-22-4
N¹,N²,N³-tris(tert-butoxycarbonyl)guanidine

Guidance literature:: With potassium hydroxide; sodium carbonate; Yield given; Multistep reaction; 1.) DMSO, 5 min; other reagent: sodium hydroxide, 2.) DMSO, 40 deg C, 60 h;
DOI:10.1021/jo9814344