4(1H)-Pteridinone,2-amino-7-methyl-(8CI,9CI)

Base Information

• Chemical Name: 4(1H)-Pteridinone,2-amino-7-methyl-(8CI,9CI)
• CAS No.: 13040-58-9
• Molecular Formula: C7H7 N5 O
• Molecular Weight: 177.165
• Hs Code.: 2933990090
• Mol file: 13040-58-9.mol

Synonyms:4(1H)-Pteridinone,2-amino-7-methyl- (8CI,9CI); 4(3H)-Pteridinone, 2-amino-7-methyl- (7CI);7-Methylpterin; NSC 24512

Chemical Property of 4(1H)-Pteridinone,2-amino-7-methyl-(8CI,9CI)

Chemical Property:

• Vapor Pressure: 9.21E-07mmHg at 25°C
• Boiling Point: 404.8°C at 760 mmHg
• Flash Point: 198.6°C
• PSA: 97.55000
• Density: 1.76g/cm³
• LogP: 0.18490
• Storage Temp.: Refrigerator
• Solubility.: Aqueous Acid (Slightly), Aqueous Base (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

7-Methylpterin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Pterin. Pterin metabolite.

Technology Process of 4(1H)-Pteridinone,2-amino-7-methyl-(8CI,9CI)

There total 29 articles about 4(1H)-Pteridinone,2-amino-7-methyl-(8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2,4,5-triaminopyrimidin-6(1H)-one sulfate monohydrate (35011-47-3) + 1-chloro-1-benzamidoacetone (88297-80-7) → 7-methylpterin (13040-58-9)

Guidance literature:

With piperidine; In water; at 20 ℃; for 168h;

DOI:10.1007/BF00956526

Reference yield: 84.0%

2,5,6-triamino-3,4-dihydro-4-pyrimidinone (1004-75-7) + N-chloroacetamidoacetone → 7-methylpterin (13040-58-9)

Guidance literature:

With triethylamine; In water; at 20 ℃; for 12h;

DOI:10.1007/BF00949233

Reference yield: 82.0%

2,4,5-triamino-6-hydroxypyrimidine sulfate (35011-47-3) + 1-tosyl-4-methylimidazolin-2-one (54972-20-2) → 7-methylpterin (13040-58-9) + toluene-4-sulfonamide (70-55-3)

Guidance literature:

With piperidine; In water; at 20 ℃; for 144h;

DOI:10.1007/BF01418017

upstream raw materials:

methyl 3-chloro-5-methyl-pyrazine-2-carboxylate

diguanidine carbonate

methanol

2,5,6-triamino-3,4-dihydro-4-pyrimidinone

Downstream raw materials:

2-acetamido-7-methylpteridin-4(3H)-one

7-methyl-1H-pteridine-2,4-dione

2-amino-1,4-dihydro-4-oxopteridine-7-carboxylic acid

7-Methyl-7,8-dihydropterin