4-BroMo-2-forMylthiophene-3-carboxylic acid

Base Information

Chemical Name:4-BroMo-2-forMylthiophene-3-carboxylic acid
CAS No.:1334640-34-4
Molecular Formula:C6H3BrO3S
Molecular Weight:235.05522
Hs Code.:
Mol file:1334640-34-4.mol

Synonyms:4-BroMo-2-forMylthiophene-3-carboxylic acid;4-bromo-2-formyl-3-thiophenecarboxylic acid

Suppliers and Price of 4-BroMo-2-forMylthiophene-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Bromo-2-formylthiophene-3-carboxylicacid 95+%
1g
$ 581.00

Chemenu
4-bromo-2-formylthiophene-3-carboxylicacid 95%
1g
$ 549.00

Arctom
4-Bromo-2-formylthiophene-3-carboxylicacid
1g
$ 483.00

Total 2 raw suppliers

Chemical Property of 4-BroMo-2-forMylthiophene-3-carboxylic acid

Chemical Property:

PSA：82.61000
LogP:2.02130

Purity/Quality:

98%min ^*data from raw suppliers

4-Bromo-2-formylthiophene-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-BroMo-2-forMylthiophene-3-carboxylic acid

There total 1 articles about 4-BroMo-2-forMylthiophene-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.2%

: 16694-17-0
4-bromo-3-thiophenecarboxylic acid

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 1334640-34-4
4-bromo-2-formyl-thiophene-3-carboxylic acid

Guidance literature:: 4-bromo-3-thiophenecarboxylic acid; With lithium diisopropyl amide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; at -78 ℃; for 1h;

N,N-dimethyl-formamide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; at -78 - 20 ℃; for 0.75h;

Reference yield: 63.5%

: 1334640-34-4
4-bromo-2-formyl-thiophene-3-carboxylic acid

: 75-03-6
ethyl iodide

: 1433203-92-9
4-bromo-2-formyl-thiophene-3-carboxylic acid ethyl ester

Guidance literature:: 4-bromo-2-formyl-thiophene-3-carboxylic acid; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

ethyl iodide; at 50 ℃; for 3h;

Reference yield:

: 1334640-34-4
4-bromo-2-formyl-thiophene-3-carboxylic acid

: 1433195-17-5
5-[2-(quinolin-2-yl)ethyl]-3-[4-(trifluoromethyl)phenyl]thieno[2,3-d]pyridazin-4(5H)-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 20 °C

1.2: 3 h / 50 °C

2.1: hydrazine hydrate / ethanol / 5 h / Reflux; Inert atmosphere

3.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 45 °C / Inert atmosphere; Cooling with ice

4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,4-dioxane; water / 0.5 h / 110 °C / Microwave irradiation

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 1,4-dioxane; ethanol; water; N,N-dimethyl-formamide;