FMOC-METHIONINE NCA

Base Information

• Chemical Name: FMOC-METHIONINE NCA
• CAS No.: 129288-42-2
• Molecular Formula: C21H19NO5S
• Molecular Weight: 397.44
• Mol file: 129288-42-2.mol

Synonyms:FMOC-METHIONINE NCA;FMOC-MET-NCA

Chemical Property of FMOC-METHIONINE NCA

Chemical Property:

• PSA: 98.21000
• LogP: 3.97390

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of FMOC-METHIONINE NCA

There total 1 articles about FMOC-METHIONINE NCA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(fluorenylmethoxy)carbonyl chloride (28920-43-6) + α-methionine-N-carboxyanhydride (15776-11-1) → Fmoc-Met-NCA (129288-42-2)

Guidance literature:

With 4-methyl-morpholine; In tetrahydrofuran; at 2 - 5 ℃; for 2h; Yield given;

DOI:10.1021/ja00176a063

Reference yield: 81.0%

Fmoc-Met-NCA (129288-42-2) + Z-Tyr(OtBu)-Lys(Boc)-OtBu → Fmoc-Met-Tyr(OtBu)-Lys(Boc)-OtBu

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 1.5h;

DOI:10.1016/0040-4039(94)02391-N

upstream raw materials:

(fluorenylmethoxy)carbonyl chloride

α-methionine-N-carboxyanhydride

Refernces