1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID

Base Information

• Chemical Name: 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID
• CAS No.: 75092-39-6
• Molecular Formula: C6H6N2O4
• Molecular Weight: 170.12
• Hs Code.: 2933199090
• Mol file: 75092-39-6.mol

Synonyms:ART-CHEM-BB B000142;AKOS B000142;1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID

Chemical Property of 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID

Chemical Property:

• PSA: 92.42000
• LogP: -0.18350

Purity/Quality:

97% ^*data from raw suppliers

1-methyl-1H-pyrazole-3,5-dicarboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID

There total 11 articles about 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

methyl ester of 1-methylpyrazole-3,5-dicarboxylic acid (33146-99-5) → 1-Methyl-1H-pyrazole-3,5-dicarboxylic acid (75092-39-6) + 3-(methoxycarbonyl)-1-methyl-1H-pyrazole-5-carboxylic acid (117860-55-6)

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃; for 24h;

DOI:10.1021/jo00263a032

Reference yield: 88.0%

diethyl 1-methylpyrazole-3,5-dicarboxylate (100852-80-0) → 1-Methyl-1H-pyrazole-3,5-dicarboxylic acid (75092-39-6)

Guidance literature:

With hydrogenchloride; In water; for 4h; Heating;

DOI:10.1016/0223-5234(87)90034-1

Reference yield:

3,5-pyrazoledicarboxylic acid (3112-31-0) → 1-Methyl-1H-pyrazole-3,5-dicarboxylic acid (75092-39-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / potassium carbonate / acetone / 24 h / Heating

2: KOH / H₂O / Heating

With potassium hydroxide; potassium carbonate; In water; acetone;

DOI:10.1021/jm00149a005

upstream raw materials:

1,3,5-trimethyl-1H-pyrazole

1,3-dimethylpyrazol-5-carboxylic acid

methyl ester of 1-methylpyrazole-3,5-dicarboxylic acid

diethyl 1-methylpyrazole-3,5-dicarboxylate

Downstream raw materials:

(3-{[5-(3-Benzyloxycarbonylamino-propylcarbamoyl)-2-methyl-2H-pyrazole-3-carbonyl]-amino}-propyl)-carbamic acid benzyl ester

(4-{[5-(4-Benzyloxycarbonylamino-butylcarbamoyl)-2-methyl-2H-pyrazole-3-carbonyl]-amino}-butyl)-carbamic acid benzyl ester

(2-{[5-(2-Benzyloxycarbonylamino-ethylcarbamoyl)-2-methyl-2H-pyrazole-3-carbonyl]-amino}-ethyl)-carbamic acid benzyl ester

1-methylpyrazole-3,5-dicarbonyl chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 75092-39-6 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send