117860-55-6

Basic information

• Product Name: 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID 3-METHYL ESTER
• Synonyms: 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID 3-METHYL ESTER;3-(Methoxycarbonyl)-1-Methyl-1H-pyrazole-5- carboxylic acid;5-Methoxycarbonyl-2-Methylpyrazole-3-carboxylic acid
• CAS NO: 117860-55-6
• Molecular Formula: C₇H₈N₂O₄
• Molecular Weight: 184.14942
• Mol File: 117860-55-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID 3-METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID 3-METHYL ESTER(117860-55-6)
• EPA Substance Registry System: 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID 3-METHYL ESTER(117860-55-6)

Safety Data

• Hazardous Substances Data: 117860-55-6(Hazardous Substances Data)

Usage

Structure

Methyl ester derivative of 1-methyl-1H-pyrazole-3,5-dicarboxylic acid

Usage

Organic synthesis, pharmaceutical research, development of drugs and bioactive molecules, materials science, and other research and industrial applications

Handling precautions

Potential hazards associated with its handling and use, should be handled with care.

Upstream product

• 33146-99-5 methyl ester of 1-methylpyrazole-3,5-dicarboxylic acid 
• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 74621-40-2 1H-pyrazole-3,5-dicarbonyl dichloride 
• 3112-31-0 3,5-pyrazoledicarboxylic acid 

Downstream Products

• 117860-57-8 methyl 5-<(benzyloxycarbonyl)amino>-1-methylpyrazole-3-carboxylate 
• 92406-53-6 methyl 5-amino-1-methyl-1H-pyrazole-3-carboxylate 
• 203792-49-8 1-methyl-3-methoxycarbonylpyrazole-3-carboxylic acid chloride 

Relevant articles and documents

METHODS OF CULTURING AND/OR EXPANDING STEM CELLS AND/OR LINEAGE COMMITTED PROGENITOR CELLS USING AMIDO COMPOUNDS

Provided are methods for expanding stem cells and/or lineage committed progenitor cells, such as hematopoietic stems cells and/or lineage committed progenitor cells, at least in part, by using compounds that antagonize AhR. The compounds are represented by formulae (I) (II) (III) (IV), wherein the letters and symbols a, b, c, d, e, f, g, Z, R1b, R2a and R2b have the meanings provided in the specification. Also provided are compositions comprising stem cells and/or lineage committed progenitor cells expanded by methods disclosed herein and methods for the treatment of diseases treatable by same.

Synthesis and Characterization of Masked Aminopyrazolecarboxylic Acid Synthons

The synthesis of the masked aminopyrazolecarboxylic acid synthons (11a,b and 12a,b) from pyrazole-3,5-dicarboxylic acid (6) and the determination of their structures by X-ray crystallography are detailed.The compounds are useful for the synthesis of polypyrazolecarboxamides analogous to the DNA minor groove binding antibiotics distamycin A and netropsin.