4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate

Base Information

Chemical Name:4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate
CAS No.:157123-02-9
Molecular Formula:C6H5F3O5S
Molecular Weight:246.164
Hs Code.:
Mol file:157123-02-9.mol

Synonyms:4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate

Suppliers and Price of 4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate

Chemical Property:

PSA：78.05000
LogP:1.76420

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate

There total 4 articles about 4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 516-09-6
4-hydroxy-3-methyl-5H-furan-2-one

: 358-23-6
trifluoromethylsulfonic anhydride

: 157123-02-9
4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at -78 ℃; for 0.75h;
DOI:10.1016/S0040-4020(01)80703-1

Reference yield: 91.0%

: 37595-74-7
N,N-phenylbistrifluoromethane-sulfonimide

: 516-09-6
4-hydroxy-3-methyl-5H-furan-2-one

: 157123-02-9
4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1016/j.tetlet.2006.04.113

Reference yield:

: 609-14-3
2-acetylpropanoic acid ethyl ester

: 157123-02-9
4-methyl-5-oxo-2,5-dihydrofuran-3-yl trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: bromine / water / 0 - 20 °C

1.2: 100 °C

2.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C

With bromine; triethylamine; In dichloromethane; water;
DOI:10.1016/j.tetlet.2011.01.036