2-chloro-1-[(E)-({1-(3-chlorophenyl)-4-methoxy-5-[2-(4-nitrophenyl)hydrazinyl]-1H-pyrazol-3-yl}carbonyl)diazenyl]ethanone

Base Information

• Chemical Name: 2-chloro-1-[(E)-({1-(3-chlorophenyl)-4-methoxy-5-[2-(4-nitrophenyl)hydrazinyl]-1H-pyrazol-3-yl}carbonyl)diazenyl]ethanone
• CAS No.: 172701-66-5
• Molecular Formula: C19H15Cl2N7O5
• Molecular Weight: 492.2723
• Mol file: 172701-66-5.mol

Synonyms:

Chemical Property of 2-chloro-1-[(E)-({1-(3-chlorophenyl)-4-methoxy-5-[2-(4-nitrophenyl)hydrazinyl]-1H-pyrazol-3-yl}carbonyl)diazenyl]ethanone

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 628°Cat760mmHg
• Flash Point: 333.6°C
• Density: 1.58g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-chloro-1-[(E)-({1-(3-chlorophenyl)-4-methoxy-5-[2-(4-nitrophenyl)hydrazinyl]-1H-pyrazol-3-yl}carbonyl)diazenyl]ethanone

There total 3 articles about 2-chloro-1-[(E)-({1-(3-chlorophenyl)-4-methoxy-5-[2-(4-nitrophenyl)hydrazinyl]-1H-pyrazol-3-yl}carbonyl)diazenyl]ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

chloroacetyl chloride (79-04-9) + 1-(3-Chloro-phenyl)-4-methoxy-5-(4-nitro-phenylazo)-1H-pyrazole-3-carboxylic acid hydrazide → 1-(3-Chloro-phenyl)-4-methoxy-5-(4-nitro-phenylazo)-1H-pyrazole-3-carboxylic acid N'-(2-chloro-acetyl)-hydrazide (172701-66-5)

Guidance literature:

at 80 ℃; for 7h;

Reference yield:

1-(3-Chloro-phenyl)-4-hydroxy-5-(4-nitro-phenylazo)-1H-pyrazole-3-carboxylic acid ethyl ester → 1-(3-Chloro-phenyl)-4-methoxy-5-(4-nitro-phenylazo)-1H-pyrazole-3-carboxylic acid N'-(2-chloro-acetyl)-hydrazide (172701-66-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 46 percent / K₂CO₃ / acetone / 12 h / Heating

2: 76 percent / hydrazine hydrate / ethanol / 8 h / Heating

3: 65 percent / 7 h / 80 °C

With potassium carbonate; hydrazine hydrate; In ethanol; acetone;

Reference yield:

1-(3-Chloro-phenyl)-4-methoxy-5-(4-nitro-phenylazo)-1H-pyrazole-3-carboxylic acid ethyl ester → 1-(3-Chloro-phenyl)-4-methoxy-5-(4-nitro-phenylazo)-1H-pyrazole-3-carboxylic acid N'-(2-chloro-acetyl)-hydrazide (172701-66-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / hydrazine hydrate / ethanol / 8 h / Heating

2: 65 percent / 7 h / 80 °C

With hydrazine hydrate; In ethanol;

upstream raw materials:

chloroacetyl chloride

Downstream raw materials:

N-[4-({5-[1-(3-Chloro-phenyl)-4-methoxy-5-(4-nitro-phenylazo)-1H-pyrazol-3-yl]-[1,3,4]oxadiazol-2-ylmethyl}-sulfamoyl)-phenyl]-acetamide