N-(4-broMophenyl)-4,4,4-trifluoro-3-oxobutanaMide

Base Information

• Chemical Name: N-(4-broMophenyl)-4,4,4-trifluoro-3-oxobutanaMide
• CAS No.: 1309681-73-9
• Molecular Formula: C10H7BrF3NO2
• Molecular Weight: 310.0672896
• Hs Code.: 2924190090
• Mol file: 1309681-73-9.mol

Synonyms:N-(4-broMophenyl)-4,4,4-trifluoro-3-oxobutanaMide

Chemical Property of N-(4-broMophenyl)-4,4,4-trifluoro-3-oxobutanaMide

Chemical Property:

• PSA: 46.17000
• LogP: 2.98210

Purity/Quality:

99% ^*data from raw suppliers

N-(4-Bromophenyl)-4,4,4-trifluoro-3-oxobutanamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-broMophenyl)-4,4,4-trifluoro-3-oxobutanaMide

There total 1 articles about N-(4-broMophenyl)-4,4,4-trifluoro-3-oxobutanaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

ethyl 4,4,4-trifluoroacetoacetate (372-31-6) + 4-bromo-aniline (106-40-1) → N-(4-bromophenyl)-4,4,4-trifluoro-3-oxobutanamide (1309681-73-9)

Guidance literature:

In acetonitrile; at 130 ℃; for 0.5h; Microwave irradiation;

DOI:10.1055/s-0030-1258440

upstream raw materials:

ethyl 4,4,4-trifluoroacetoacetate

4-bromo-aniline

Refernces

• 1、 -. "Bicyclic androgen and progesterone receptor modulator compounds and methods". . . Retrieved 2008/06/13.