Methyl 4-chloro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate

Base Information

Chemical Name:Methyl 4-chloro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate
CAS No.:710350-72-4
Molecular Formula:C14H18BClO4
Molecular Weight:296.559
Hs Code.:2934999090
Mol file:710350-72-4.mol

Synonyms:(2-CHLORO-5-(METHOXYCARBONYL)PHENYL)BORONIC ACID PINACOL ESTER;Methyl 4-chloro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate;Methyl 4-chloro-3-(hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boranyl)benzoate;4-Chloro-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoic acid methyl ester;Benzoic acid, 4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester

Suppliers and Price of Methyl 4-chloro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-5-methoxycarbonylphenylboronicacidpinacolester
1g
$ 390.00

Crysdot
Methyl4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 95+%
5g
$ 663.00

Chemcia Scientific
4-Chloro-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoicacidmethylester 95%
5 G
$ 705.00

AOBChem
Methyl4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 97%
5g
$ 762.00

Ambeed
Methyl4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 97%
1g
$ 246.00

Ambeed
Methyl4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 97%
250mg
$ 99.00

Ambeed
Methyl4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 97%
100mg
$ 67.00

Alichem
Methyl4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
5g
$ 976.67

Total 9 raw suppliers

Chemical Property of Methyl 4-chloro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate

Chemical Property:

PSA：44.76000
LogP:2.42580
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-5-methoxycarbonylphenylboronicacidpinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Chloro-5-methoxycarbonylphenylboronic acid pinacol ester

Technology Process of Methyl 4-chloro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate

There total 4 articles about Methyl 4-chloro-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 365526-34-7
methyl 4-chloro-3-iodo-benzoate

: 73183-34-3
bis(pinacol)diborane

: 710350-72-4
methyl 4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In dimethyl sulfoxide; at 80 ℃; for 18h; Inert atmosphere;

Reference yield:

: 42860-10-6
3-bromo-4-chlorobenzoic acid

: 710350-72-4
methyl 4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: acetyl chloride / 12 h / 0 - 20 °C

2: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 12 h / 95 °C

With potassium acetate; acetyl chloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide;

Reference yield:

: 42860-04-8
4-chloro-3-iodobenzoic acid

: 710350-72-4
methyl 4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 4 h / 80 °C

2: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / dimethyl sulfoxide / 18 h / 80 °C / Inert atmosphere

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sulfuric acid; potassium acetate; In dimethyl sulfoxide;