7-(CARBOXYMETHOXY)-4-METHYLCOUMARIN

Base Information

• Chemical Name: 7-(CARBOXYMETHOXY)-4-METHYLCOUMARIN
• CAS No.: 64700-15-8
• Molecular Formula: C12H10 O5
• Molecular Weight: 234.208
• Hs Code.: 2932209090
• Mol file: 64700-15-8.mol

Synonyms:Aceticacid, [(4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]- (7CI,9CI);7-(Carboxymethoxy)-4-methylcoumarin

Chemical Property of 7-(CARBOXYMETHOXY)-4-METHYLCOUMARIN

Chemical Property:

• Vapor Pressure: 3.36E-09mmHg at 25°C
• Melting Point: 206-208 °C(lit.)
• Boiling Point: 458.5oC at 760 mmHg
• PKA: 3.05±0.10(Predicted)
• Flash Point: 183oC
• PSA: 76.74000
• Density: 1.375±0.06 g/cm3(Predicted)
• LogP: 1.56480

Purity/Quality:

97% ^*data from raw suppliers

7-(Carboxymethoxy)-4-methylcoumarin ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 7-(Carboxymethoxy)-4-methylcoumarin (CMC) was used in the preparation of poly(4-vinyl pyridine)-CMC, photosensitive polymer and 3-chloro-7-[(chlorocarbonyl)methoxy]-4-methylcoumarin.

Technology Process of 7-(CARBOXYMETHOXY)-4-METHYLCOUMARIN

There total 1 articles about 7-(CARBOXYMETHOXY)-4-METHYLCOUMARIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-oxo-1-phenylpropan-2-yl 2-(4-methylcoumarin-7-yloxy)acetate (1394863-39-8) → 7-(carboxymethoxy)-4-methylcoumarin (64700-15-8) + 1-phenyl-propan-1-one (93-55-0)

Guidance literature:

With methanol; potassium chloride; sodium chloride; calcium chloride; sodium hydroxide; magnesium chloride; N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid; In water; pH=7.2; Wavelength; Quantum yield; Kinetics; Photolysis;

DOI:10.1016/j.tet.2012.06.100

Reference yield: 100.0%

7-(carboxymethoxy)-4-methylcoumarin (64700-15-8) → 7-<(chlorocarbonyl)methoxy>-4-methylcoumarin (91454-65-8)

Guidance literature:

With thionyl chloride; In chloroform; for 2h; Heating;

DOI:10.1016/S0040-4020(02)00442-8

Reference yield: 82.0%

4-amino-1-benzylpiperidine (50541-93-0) + 7-(carboxymethoxy)-4-methylcoumarin (64700-15-8) → N-(1-benzylpiperidin-4-yl)-2-((4-methyl-2-oxo-2Hchromen-7-yl)oxy)acetamide

Guidance literature:

7-(carboxymethoxy)-4-methylcoumarin; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 20 ℃; for 0.5h;

4-amino-1-benzylpiperidine; In acetonitrile; at 20 ℃; for 24h;

DOI:10.1002/ardp.201700076

upstream raw materials:

1-oxo-1-phenylpropan-2-yl 2-(4-methylcoumarin-7-yloxy)acetate

Downstream raw materials:

7-<(chlorocarbonyl)methoxy>-4-methylcoumarin

methyl 2-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]acetate

2-[N-(4-methyl-2-oxobenzo[b]pyran-7-yloxyacetyl)-2-methoxyphenylaminomethylene]-2,3-dihydrobenzo[b]thiophen-3-one

2-[N-(4-methyl-2-oxobenzo[b]pyran-7-yloxyacetyl)-N-(2-p-tolylsulfonylaminophenyl)aminomethylene]-2,3-dihydrobenzo[b]thiophen-3-one