2-Phenyl-4H-pyrazino[2,3-d][1,3]oxazin-4-one

Base Information

Chemical Name:2-Phenyl-4H-pyrazino[2,3-d][1,3]oxazin-4-one
CAS No.:155513-85-2
Molecular Formula:C12H7N3O2
Molecular Weight:225.20288
Hs Code.:
DSSTox Substance ID:DTXSID70704568
Nikkaji Number:J584.010D
Wikidata:Q82637024
Mol file:155513-85-2.mol

Synonyms:2-Phenyl-4H-pyrazino[2,3-d][1,3]oxazin-4-one;155513-85-2;2-phenylpyrazino[2,3-d][1,3]oxazin-4-one;DTXSID70704568;FT-0734174

Suppliers and Price of 2-Phenyl-4H-pyrazino[2,3-d][1,3]oxazin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 2-Phenyl-4H-pyrazino[2,3-d][1,3]oxazin-4-one

Chemical Property:

Melting Point:199 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling Point:382.6±22.0 °C(Predicted)
PKA:-2.30±0.20(Predicted)
PSA：68.88000
Density:1.42±0.1 g/cm3(Predicted)
LogP:1.64500
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:225.053826475
Heavy Atom Count:17
Complexity:337

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC3=NC=CN=C3C(=O)O2

Technology Process of 2-Phenyl-4H-pyrazino[2,3-d][1,3]oxazin-4-one

There total 4 articles about 2-Phenyl-4H-pyrazino[2,3-d][1,3]oxazin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 93044-39-4
3-benzoylamino-pyrazine-2-carboxylic acid methyl ester

: 155513-85-2
2-Phenylpyrazino<2,3-d><3,1>oxazin-4-one

Guidance literature:: With dibromotetrachloroethane; triethylamine; triphenylphosphine; In toluene; at 80 ℃; for 6h;
DOI:10.1055/s-1994-25487

Reference yield: 30.0%

: 5424-01-1
3-aminopyrazinoic acid

: 98-88-4
benzoyl chloride

: 155513-85-2
2-Phenylpyrazino<2,3-d><3,1>oxazin-4-one

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1016/j.molstruc.2005.01.061

Reference yield:

: 16298-03-6
Methyl 3-amino-2-pyrazinecarboxylate

: 155513-85-2
2-Phenylpyrazino<2,3-d><3,1>oxazin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 50 °C

2: 98percent hydrazine hydrate / dioxane; propan-2-ol / 0.5 h / Heating

3: 71 percent / Ph₃P, Et₃N, dibromotetrachloroethane / toluene / 6 h / 80 °C

With pyridine; dibromotetrachloroethane; hydrazine hydrate; triethylamine; triphenylphosphine; In 1,4-dioxane; isopropyl alcohol; toluene;
DOI:10.1055/s-1994-25487