3-TERT-BUTOXYPYRIDINE

Base Information

• Chemical Name: 3-TERT-BUTOXYPYRIDINE
• CAS No.: 31776-90-6
• Molecular Formula: C9H13NO
• Molecular Weight: 151.208
• Hs Code.: 2933399990
• Mol file: 31776-90-6.mol

Synonyms:3-TERT-BUTOXYPYRIDINE

Chemical Property of 3-TERT-BUTOXYPYRIDINE

Chemical Property:

• Boiling Point: 213.5±13.0 °C(Predicted)
• PKA: 4.77±0.10(Predicted)
• PSA: 22.12000
• Density: 0.967±0.06 g/cm3(Predicted)
• LogP: 2.25890
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

≥98% ^*data from raw suppliers

3-(tert-Butoxy)pyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-TERT-BUTOXYPYRIDINE

There total 2 articles about 3-TERT-BUTOXYPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

3-Bromopyridine (626-55-1,163928-56-1) + sodium t-butanolate (865-48-5) → pyridine (110-86-1) + 3,3'-bipyridine (581-46-4) + 3-tert-butoxy-pyridine (31776-90-6)

Guidance literature:

With palladium diacetate; tri-tert-butyl phosphine; In xylene; at 120 ℃; for 22h;

DOI:10.1016/S0040-4039(99)01855-9

Reference yield: 7.0%

furan (110-00-9) + 3-bromo-4-(trimethylsilyl)pyridine (134391-67-6) → 5,8-endoxo-5,8-dihydroisoquinoline (40247-40-3) + 3-tert-butoxy-pyridine (31776-90-6) + 4-bromopyridin (1120-87-2) + 4-Brom-3-(trimethylsilyl)pyridin (134391-73-4)

Guidance literature:

With potassium tert-butylate; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 0 ℃; for 2h;

upstream raw materials:

furan

3-bromo-4-(trimethylsilyl)pyridine

3-Bromopyridine

sodium t-butanolate