Sodium tert-butoxide

Base Information

• Chemical Name: Sodium tert-butoxide
• CAS No.: 865-48-5
• Molecular Formula: C4H9NaO
• Molecular Weight: 96.1046
• Hs Code.: 2905.19
• Mol file: 865-48-5.mol

Synonyms:2-Propanol,2-methyl-, sodium salt (9CI);Sodium tert-butoxide (6CI);tert-Butyl alcohol,sodium salt (8CI);2-Methyl-2-propanol sodium salt;Sodium tert-butanolate;Sodium tert-butylate;tert-Butanol sodium salt;tert-Butoxysodium;Sodium tert-butoxide;

Chemical Property of Sodium tert-butoxide

Chemical Property:

• Appearance/Colour: white to light tan crystalline powder
• Vapor Pressure: 46mmHg at 25°C
• Melting Point: 180 °C
• Refractive Index: n20/D1.413
• Boiling Point: 84.6 °C at 760 mmHg
• Flash Point: 11.7 °C
• PSA: 23.06000
• Density: 1,104 g/cm3
• LogP: 1.21540
• Storage Temp.: Flammables area
• Sensitive.: Air Sensitive & Hygroscopic
• Solubility.: very slightly in Tetrahydrofuran
• Water Solubility.: reacts

Purity/Quality:

99%, ^*data from raw suppliers

Sodium tert butoxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, C, Xi
• Hazard Codes: F,C,Xi
• Statements: 11-14-34-37-35-36/37/38-40-19
• Safety Statements: 26-36/37/39-43-45-7/8-8-16-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium tert-butoxide is used as a strong base and a non-nucleophilic base. In organic synthesis, it serves as an intermediate in various reactions like condensation, rearrangement and ring-opening. Further, it finds use in agrochemicals, pharmaceuticals, colorants, aroma chemicals, detergents and biodiesel. It acts as a catalyst in polymerization and isomerization reactions.

Technology Process of Sodium tert-butoxide

There total 8 articles about Sodium tert-butoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

tert-butyl alcohol (75-65-0) → sodium t-butanolate (865-48-5)

Guidance literature:

With sodium amide; In water; toluene; at 105 ℃; for 2h; Temperature; Solvent;

Reference yield:

→ cis,trans methyl 2,2-dimethyl-3-(2',2'-dichlorovinyl)-cyclopropanecarboxylate (61898-95-1) + sodium t-butanolate (865-48-5)

Guidance literature:

Reference yield:

1-methyl-pyrrolidin-2-one (872-50-4,26138-58-9) + tert-butyl alcohol (75-65-0) → sodium t-butanolate (865-48-5)

Guidance literature:

upstream raw materials:

tert-butyl alcohol

1-methyl-pyrrolidin-2-one

Downstream raw materials:

5-hydroxy-2-oxo-cyclohexanecarboxylic acid ethyl ester

tert-butyl acetoacetate

tris(tert-butoxy)silanol

O{Si(Ot-bu)3}2

Refernces

• 1、 -. "Novel process for preparing sodium tert-butoxide by using xylene as solvent". Paragraph 0027-0084. . Retrieved 2021/05/29.
• 2、 -. "Sodium tert-butoxide production technology". Paragraph 0002-0003. . Retrieved 2017/08/29.