potassiuM 1-tert-butyl-3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridin-2-olate

Base Information

Chemical Name:potassiuM 1-tert-butyl-3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridin-2-olate
CAS No.:1246647-79-9
Molecular Formula:C₁₃H₁₅N₂O₃*K
Molecular Weight:286.372
Hs Code.:
Mol file:1246647-79-9.mol

Synonyms:potassiuM 1-tert-butyl-3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridin-2-olate

Suppliers and Price of potassiuM 1-tert-butyl-3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridin-2-olate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
POTASSIUM 1-TERTBUTYL-3-(METHOXYCARBONYL)-1H-PYRROLO-[2,3-B]-PYRIDIN-2-OLATE 95.00%
5MG
$ 502.84

Total 1 raw suppliers

Chemical Property of potassiuM 1-tert-butyl-3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridin-2-olate

Chemical Property:

PSA：67.18000
LogP:2.72170

Purity/Quality:: POTASSIUM 1-TERTBUTYL-3-(METHOXYCARBONYL)-1H-PYRROLO-[2,3-B]-PYRIDIN-2-OLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of potassiuM 1-tert-butyl-3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridin-2-olate

There total 1 articles about potassiuM 1-tert-butyl-3-(Methoxycarbonyl)-1H-pyrrolo[2,3-b]pyridin-2-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1246733-24-3
methyl 1-(tert-butyl)-2-hydroxy-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

: 1246647-79-9
C₁₃H₁₅N₂O₃^(1-)*K⁽¹⁺⁾

Guidance literature:: With potassium carbonate; potassium hydroxide; In tetrahydrofuran; n-heptane; water; at 10 - 20 ℃; pH=12.5 - 13.5; Industry scale;

Reference yield:

: 1246647-79-9
C₁₃H₁₅N₂O₃^(1-)*K⁽¹⁺⁾

: 957118-49-9
[3H]-MK 3207

Guidance literature:: Multi-step reaction with 6 steps

1.1: acetic acid / methanol / 0.08 h / 6 °C / Industry scale

2.1: potassium hydroxide / toluene; water / 0.33 h / 12.5 °C / Industry scale; Inert atmosphere

2.2: 1.65 h / 12.5 - 14.6 °C / Industry scale; Inert atmosphere

3.1: (9R)-1-[3,5-bis(trifluoromethyl)benzyl]cinchonan-1-ium-9-ol bromide / toluene; water / 16 h / 10 °C / Industry scale; Inert atmosphere

4.1: toluene / 6.67 h / 90 °C / Industry scale

5.1: hydrogen / palladium 10% on activated carbon / toluene; methanol / 20 - 27 °C / 3102.97 Torr / Industry scale

5.2: 20 °C / pH 6.3 / Industry scale

6.1: benzotriazol-1-ol / N,N-dimethyl-formamide / 0.5 h / 17 - 20 °C / Industry scale; Inert atmosphere

6.2: 39.5 h / 14 - 23 °C / Industry scale; Inert atmosphere

With hydrogen; benzotriazol-1-ol; acetic acid; potassium hydroxide; (9R)-1-[3,5-bis(trifluoromethyl)benzyl]cinchonan-1-ium-9-ol bromide; palladium 10% on activated carbon; In methanol; water; N,N-dimethyl-formamide; toluene;

Reference yield:

: 1246647-79-9
C₁₃H₁₅N₂O₃^(1-)*K⁽¹⁺⁾

: 1260403-57-3
(R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / methanol / 0.08 h / 6 °C / Industry scale

2.1: potassium hydroxide / toluene; water / 0.33 h / 12.5 °C / Industry scale; Inert atmosphere

2.2: 1.65 h / 12.5 - 14.6 °C / Industry scale; Inert atmosphere

3.1: (9R)-1-[3,5-bis(trifluoromethyl)benzyl]cinchonan-1-ium-9-ol bromide / toluene; water / 16 h / 10 °C / Industry scale; Inert atmosphere

With acetic acid; potassium hydroxide; (9R)-1-[3,5-bis(trifluoromethyl)benzyl]cinchonan-1-ium-9-ol bromide; In methanol; water; toluene;