(R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one

Base Information

Chemical Name:(R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one
CAS No.:1260403-57-3
Molecular Formula:C₃₃H₃₃N₃O
Molecular Weight:487.645
Hs Code.:

Synonyms:(R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one

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Technology Process of (R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one

There total 19 articles about (R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 1246733-24-3
methyl 1-(tert-butyl)-2-hydroxy-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

: 1260403-55-1
[2-(chloromethyl)-4-(dibenzylamino)phenyl]methanol hydro chloride

: 1260403-57-3
(R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one

Guidance literature:: With (1S,2S,4S,5R)-1-(3,5-bis(trifluoromethyl)benzyl)-2-((R)-hydroxy(quinolin-4-yI)methyl)-5-vinylquinuclidin-1-ium bromide; water; sodium hydroxide; In toluene; at 20 ℃; for 3.25h; Inert atmosphere;

Reference yield: 52.0%

: 1246733-24-3
methyl 1-(tert-butyl)-2-hydroxy-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

: 1260403-55-1
C₂₂H₂₂ClNO*(x)ClH

: 1260403-57-3
(R)-1’-(tert-butyl)-5-(dibenzylamino)-1,3-dihydrospiro[indene-2,3’-pyrrolo[2,3-b]pyridin]-2’(1’H)-one

Guidance literature:: C₂₂H₂₂ClNO*(x)ClH; With sodium hydroxide; In water; toluene; at 20 ℃; for 0.0833333h; Inert atmosphere;

methyl 1-(tert-butyl)-2-hydroxy-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; In water; toluene; for 0.416667h; Inert atmosphere;

With C₂₈H₂₇F₆N₂O⁽¹⁺⁾; In water; toluene; at 20 ℃; for 3h; Inert atmosphere;