4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine

Base Information

Chemical Name:4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine
CAS No.:55115-80-5
Molecular Formula:C9H4ClN3S
Molecular Weight:221.67
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90381476
Wikidata:Q82172325
Mol file:55115-80-5.mol

Synonyms:4-chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine;55115-80-5;6-chloro-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene;C9H4ClN3S;SCHEMBL9042411;DTXSID90381476;QCUXTBKFKCTJIQ-UHFFFAOYSA-N;AKOS005073912;BB 0262782;CS-0366736;4-Chloro-pyrido[3`,2`:4,5]thieno[3,2-d]pyrimidine;4-chloropyrido[3',2';4,5]thieno[3,2-d]pyrimidine;4-chloropyrido [3',2';4-chloropyrido[3', 2';6-chloro-8-thia-3,5,10-triazatricyclo[7.4.0.0?,?]trideca-1(9),2(7),3,5,10,12-hexaene

Suppliers and Price of 4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine
500mg
$ 1188.00

American Custom Chemicals Corporation
4-CHLOROPYRIDO[3',2':4,5]THIENO[3,2-D]PYRIMIDINE 95.00%
500MG
$ 1503.81

Crysdot
4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine 95+%
1g
$ 888.00

Matrix Scientific
4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine >95%
500mg
$ 843.00

TRC
4-Chloropyrido[3'',2'':4,5]thieno[3,2-d]pyrimidine
10mg
$ 90.00

TRC
4-Chloropyrido[3'',2'':4,5]thieno[3,2-d]pyrimidine
50mg
$ 350.00

Total 4 raw suppliers

Chemical Property of 4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine

Chemical Property:

PSA：66.91000
LogP:2.89290
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:220.9814460
Heavy Atom Count:14
Complexity:228

Purity/Quality:

98%min ^*data from raw suppliers

4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=C(N=C1)SC3=C2N=CN=C3Cl

Technology Process of 4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine

There total 6 articles about 4-Chloropyrido[3',2':4,5]thieno[3,2-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 55115-79-2
Pyrido<3',2':4,5>thieno<3,2-d>pyrimidin-4(1H)-one

: 55115-80-5
4-chloropyrido[3',2';4,5]thieno[3,2-d]pyrimidine

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In 1,2-dichloro-ethane; at 85 ℃; for 2h;
DOI:10.1021/jm9903949

Reference yield:

: 6602-54-6
2-chloro-3-pyridinecarbonitrile

: 55115-80-5
4-chloropyrido[3',2';4,5]thieno[3,2-d]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / dimethylsulfoxide / 25 °C

1.2: 89 percent / dimethylsulfoxide / 3 h / 25 °C

2.1: 73 percent / 5 h / 135 - 190 °C

3.1: 96 percent / oxalyl chloride; DMF / 1,2-dichloro-ethane / 2 h / 85 °C

With oxalyl dichloride; sodium hydride; N,N-dimethyl-formamide; In dimethyl sulfoxide; 1,2-dichloro-ethane; 1.1: Metallation / 1.2: Cyclization / 2.1: Cyclization / 3.1: Substitution;
DOI:10.1021/jm9903949

Reference yield:

: 52505-46-1
ethyl 3-aminothieno[2,3-b]pyridine-2-carboxylate

: 55115-80-5
4-chloropyrido[3',2';4,5]thieno[3,2-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / 5 h / 135 - 190 °C

2: 96 percent / oxalyl chloride; DMF / 1,2-dichloro-ethane / 2 h / 85 °C

With oxalyl dichloride; N,N-dimethyl-formamide; In 1,2-dichloro-ethane; 1: Cyclization / 2: Substitution;
DOI:10.1021/jm9903949