Chroman-8-sulfonyl chloride , 97%

Base Information

• Chemical Name: Chroman-8-sulfonyl chloride , 97%
• CAS No.: 1048970-15-5
• Molecular Formula: C₉H₉ClO₃S
• Molecular Weight: 232.688
• Mol file: 1048970-15-5.mol

Synonyms:Chroman-8-sulfonyl chloride , 97%

Chemical Property of Chroman-8-sulfonyl chloride , 97%

Chemical Property:

• PSA: 51.75000
• LogP: 3.01990

Purity/Quality:

98%min ^*data from raw suppliers

Chroman-8-sulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Chroman-8-sulfonyl chloride , 97%

There total 1 articles about Chroman-8-sulfonyl chloride , 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

8-bromo-3,4-dihydro-2H-1-benzopyran (3722-78-9) → chromane-8-sulfonyl chloride (1048970-15-5)

Guidance literature:

8-bromo-3,4-dihydro-2H-1-benzopyran; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

With sulfur dioxide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 0.05h;

With N-chloro-succinimide; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

chromane-8-sulfonyl chloride (1048970-15-5) + tert-butyl (3-amino-2,6-difluorophenyl)carbamate (535170-20-8) → C20H22F2N2O5S

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1002/bkcs.10917

upstream raw materials:

8-bromo-3,4-dihydro-2H-1-benzopyran