Norbraylin

Base Information

Chemical Name:Norbraylin
CAS No.:60796-64-7
Molecular Formula:C14H12O4
Molecular Weight:244.24
Hs Code.:2932999099
DSSTox Substance ID:DTXSID401346491
Nikkaji Number:J18.346F
Wikidata:Q104251749
Metabolomics Workbench ID:130835
ChEMBL ID:CHEMBL3235995
Mol file:60796-64-7.mol

Synonyms:Norbraylin;60796-64-7;6-Hydroxy-8,8-dimethylpyrano[2,3-f]chromen-2-one;CHEMBL3235995;6-Hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one;orbraylin;DTXSID401346491;HY-N3180;BDBM50008739;AKOS027257455;FS-8867;CS-0023514;E88723

Suppliers and Price of Norbraylin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Norbraylin 95+%
10mg
$ 660.00

Arctom
Norbraylin ≥98%
5mg
$ 463.00

Total 19 raw suppliers

Chemical Property of Norbraylin

Chemical Property:

Boiling Point:471.1±45.0 °C(Predicted)
PKA:8.34±0.40(Predicted)
PSA：59.67000
Density:1.319±0.06 g/cm3(Predicted)
LogP:2.68280
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:244.07355886
Heavy Atom Count:18
Complexity:424

Purity/Quality:

≥98% ^*data from raw suppliers

Norbraylin 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C=CC2=C3C(=CC(=C2O1)O)C=CC(=O)O3)C

Technology Process of Norbraylin

There total 3 articles about Norbraylin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 305-01-1
aesculetin

: 1740-74-5
1,1-diethoxy-3-methyl-2-butene

: 60796-64-7
norbraylin

: Cedrecoumarin A

Guidance literature:: With 3-Methylpyridine; In 5,5-dimethyl-1,3-cyclohexadiene; at 160 ℃; for 6h;
DOI:10.1016/j.bmcl.2019.126759

Reference yield: 44.0%

: 1111-97-3
3-chloro-3-methylbut-1-yne

: 305-01-1
aesculetin

: 60796-64-7
norbraylin

: 3,3-dimethyl-2-methylene-2,3-dihydro-7H-[1,4]dioxino[2,3-g]chromen-7-one

Guidance literature:: With caesium carbonate; In acetone; at 100 ℃; for 3h; Microwave irradiation;
DOI:10.1002/jhet.3376

Reference yield:

: 92-61-5
7-hydroxy-6-methoxy-2H-1-benzopyran-2-one

: 60796-64-7
norbraylin

: Cedrecoumarin A

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine hydrochloride / 150 °C

2: 3-Methylpyridine / 5,5-dimethyl-1,3-cyclohexadiene / 6 h / 160 °C

With 3-Methylpyridine; pyridine hydrochloride; In 5,5-dimethyl-1,3-cyclohexadiene;
DOI:10.1016/j.bmcl.2019.126759