92-61-5Relevant articles and documents
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Braymer et al.
, p. 163 (1960)
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Coumarins from Astragalus asper
Guzhva
, p. 767 - 768 (2008)
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COUMARIN COMPOSITION OF Haplophyllum bungei
Abyshev, A. Z.,Gashimov, N. F.
, p. 615 - 616 (1982)
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A COUMARIN GLUCOSIDE FROM XEROMPHIS OBOVATA
Sibanda, S.,Ndengu, B.,Multari, G.,Pompi, V.,Galeffi, C.
, p. 1550 - 1552 (1989)
From root bark of Xeromphis obovata three coumarins have been isolated: scopoletin, its 7-β-D-glucopyranoside (scopolin) and the new β-D-apiosyl-(1" -> 6)-β-D-glucopyranoside of scopoletin, named xeroboside.Also two iridoids, deacetylasperulosidic acid methyl ester and gardenoside, have been isolated and identified as the corresponding acetyl derivetives. Key Word Index-Xeromphis obovata; Rubiaceae; coumarins; iridoids; xeroboside.
COUMARINS OF Ptarmica bisserata
Davidyats, E. S.
, p. 233 (1982)
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Scopoletin benzene sulfonyl furazan oxynitride derivatives as well as preparation method and application thereof
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Paragraph 0039; 0048-0052, (2020/06/20)
The invention belongs to the field of biological medicines, and discloses scopoletin benzene sulfonyl furazan oxynitride derivatives as shown in a formula I, wherein R is selected from H, acetamido and amino, X is selected from -(CH2)n-, and n is an integer of 2-6. Compared with scopoletin, the derivatives have a stronger proliferation inhibition effect on MDA-MB-231, MCF-7, HepG2 and A549 cell strains, the proliferation inhibition effect on tumor cells is remarkably superior to that of scopoletin, and the derivatives are expected to become a new anti-tumor drug. The invention also discloses an application of the derivatives in the preparation of antitumor drugs.
Escoparone chemical whole synthetic method
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Paragraph 0032; 0039-0041; 0045; 0052-0054, (2019/05/15)
The invention discloses escoparone chemical whole synthetic method, which belongs to the technical field of chemical synthesis, escoparone chemical full-synthetic method is 2, 4, 5 - trimethoxybenzaldehyde de-methyl generating 4 - dihydroxy - 5 - methoxybenzaldehyde; 4 - dihydroxy - 5 - methoxy benzaldehyde with malonic acid to generate the cyclization reaction to produce the 3 - carboxyl scopolamine lactone; 3 - carboxyl scopolamine lactone by microwave auxiliary decarboxylative generating scopolamine lactone; scopolamine lactone by methylation get escoparone, aims to solve the low efficiency of the plant extract, the disadvantage of low yield and the synthetic yield is low, high cost, is not suitable for the industrial application of the shortcomings.