Technology Process of N''-[2-(3,4-Dihydroxyphenyl)ethenyl]guanidine
There total 5 articles about N''-[2-(3,4-Dihydroxyphenyl)ethenyl]guanidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
acetonitrile;
at 100 ℃;
for 0.333333h;
Microwave irradiation;
DOI:10.1016/j.tet.2015.09.003
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N-iodo-succinimide; lithium acetate / acetonitrile; water / 3 h / 20 °C
2: copper(l) iodide; potassium phosphate; N,N`-dimethylethylenediamine / acetonitrile / 0.58 h / 65 °C / Inert atmosphere; Microwave irradiation
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / -10 °C
4: trifluoroacetic acid / acetonitrile / 0.33 h / 100 °C / Microwave irradiation
With
potassium phosphate; N-iodo-succinimide; copper(l) iodide; lithium acetate; tetrabutyl ammonium fluoride; trifluoroacetic acid; N,N`-dimethylethylenediamine;
In
tetrahydrofuran; water; acetonitrile;
DOI:10.1016/j.tet.2015.09.003
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine / dichloromethane / 18 h / 20 °C
2: N-iodo-succinimide; lithium acetate / acetonitrile; water / 3 h / 20 °C
3: copper(l) iodide; potassium phosphate; N,N`-dimethylethylenediamine / acetonitrile / 0.58 h / 65 °C / Inert atmosphere; Microwave irradiation
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.08 h / -10 °C
5: trifluoroacetic acid / acetonitrile / 0.33 h / 100 °C / Microwave irradiation
With
potassium phosphate; N-iodo-succinimide; copper(l) iodide; lithium acetate; tetrabutyl ammonium fluoride; triethylamine; trifluoroacetic acid; N,N`-dimethylethylenediamine;
In
tetrahydrofuran; dichloromethane; water; acetonitrile;
DOI:10.1016/j.tet.2015.09.003