erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride

Base Information

Chemical Name:erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride
CAS No.:81408-49-3
Molecular Formula:C₁₄H₂₃N₅O*ClH
Molecular Weight:313.83
Hs Code.:
UNII:D94V1GC7I3,UGQ2ATP3NK
DSSTox Substance ID:DTXSID9040473
Wikipedia:EHNA
ChEMBL ID:CHEMBL1257094
Mol file:81408-49-3.mol

Synonyms:6-amino beta-hexyl alpha-methyl-9H-purine-9-ethanol;9-(2-hydroxy-3-nonyl)adenine;9-(2-hydroxy-3-nonyl)adenine hydrochloride;9-(2-hydroxy-3-nonyl)adenine monohycrochloride;9-(2-hydroxy-3-nonyl)adenine monohycrochloride, (erythro-R*,S*)-isomer;9-(2-hydroxy-3-nonyl)adenine oxalate (2:1);9-(2-hydroxy-3-nonyl)adenine oxalate (2:1), (erythro-R*,R*)-isomer;9-(2-hydroxy-3-nonyl)adenine, (R*,S*)-(+-)-isomer;9-(2-hydroxy-3-nonyl)adenine, (R*,S*)-isomer;9-(2-hydroxy-3-nonyl)adenine, (R-(R*,R*))-isomer;9-(2-hydroxy-3-nonyl)adenine, (R-(R*,S*))-isomer;9-(2-hydroxy-3-nonyl)adenine, (S-(R*,R*))-isomer;9-(2-hydroxy-3-nonyl)adenine, (S-(R*,S*))-isomer;EHNA

Suppliers and Price of erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride

Chemical Property:

Melting Point:163-170°C
PSA：89.85000
LogP:3.68400
Storage Temp.:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:313.1669381
Heavy Atom Count:21
Complexity:291

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCC(C(C)O)N1C=NC2=C(N=CN=C21)N.Cl
Isomeric SMILES:CCCCCC[C@@H]([C@@H](C)O)N1C=NC2=C(N=CN=C21)N.Cl

Technology Process of erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride

There total 13 articles about erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 81408-48-2
(2R,3S)-3-(adenin-9-yl)-2-O-benzyl-2-nonanol

: 81408-49-3
(2R,3S)-3-(adenin-9-yl)-2-nonanol hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In isopropyl alcohol; for 96h; under 2585.7 Torr;
DOI:10.1021/jo00132a039

Reference yield: 54.0%

: 229308-71-8
9-{(S)-1-[(R)-1-(Tetrahydro-pyran-2-yloxy)-ethyl]-heptyl}-9H-purin-6-ylamine

: 81408-49-3
(2R,3S)-3-(adenin-9-yl)-2-nonanol hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; for 12h; Ambient temperature;
DOI:10.1016/S0957-4166(99)00059-2

Reference yield:

: 81408-40-4
(2R,3R)-2-O-benzyl-2,3-nonanediol

: 81408-49-3
(2R,3S)-3-(adenin-9-yl)-2-nonanol hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 48 h / Ambient temperature

2: 1.) NaH / 1.) N,N-dimethylformamide, room temperature, 24 h, 2.) N,N-dimethylformamide, 50 deg C, 7 days

3: 80 percent / H₂, conc. HCl / 10percent Pd/C / propan-2-ol / 96 h / 2585.7 Torr

With pyridine; hydrogenchloride; hydrogen; sodium hydride; palladium on activated charcoal; In isopropyl alcohol;
DOI:10.1021/jo00132a039