2H-INDAZOLE, 5-BROMO-3-IODO-2-[[2-(TRIMETHYLSILYL)ETHOXY]METHYL]-

Base Information

Chemical Name:2H-INDAZOLE, 5-BROMO-3-IODO-2-[[2-(TRIMETHYLSILYL)ETHOXY]METHYL]-
CAS No.:1012104-27-6
Molecular Formula:C₁₃H₁₈BrIN₂OSi
Molecular Weight:453.193
Hs Code.:
Mol file:1012104-27-6.mol

Synonyms:2H-INDAZOLE, 5-BROMO-3-IODO-2-[[2-(TRIMETHYLSILYL)ETHOXY]METHYL]-

Suppliers and Price of 2H-INDAZOLE, 5-BROMO-3-IODO-2-[[2-(TRIMETHYLSILYL)ETHOXY]METHYL]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
5-Bromo-3-iodo-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole 95%+
1g
$ 2288.00

Chemenu
5-Bromo-3-iodo-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole 95%+
250mg
$ 992.00

Chemenu
5-Bromo-3-iodo-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole 95%+
100mg
$ 595.00

Total 5 raw suppliers

Chemical Property of 2H-INDAZOLE, 5-BROMO-3-IODO-2-[[2-(TRIMETHYLSILYL)ETHOXY]METHYL]-

Chemical Property:

Boiling Point:447.9±40.0 °C(Predicted)
PKA:-0.97±0.30(Predicted)
PSA：27.05000
Density:1.65±0.1 g/cm3(Predicted)
LogP:4.71570

Purity/Quality:

≥95% ^*data from raw suppliers

5-Bromo-3-iodo-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2H-INDAZOLE, 5-BROMO-3-IODO-2-[[2-(TRIMETHYLSILYL)ETHOXY]METHYL]-

There total 2 articles about 2H-INDAZOLE, 5-BROMO-3-IODO-2-[[2-(TRIMETHYLSILYL)ETHOXY]METHYL]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 459133-66-5
5-bromo-3-iodo-1H-indazole

: 918440-14-9
5-bromo-3-iodo-1-[2-(trimethylsilanyl)ethoxymethyl]-1H-indazole

: 1012104-27-6
5-bromo-3-iodo-2-(2-trimethylsilanyl-ethoxymethyl)-1H-indazole

Guidance literature:: 5-bromo-3-iodo-1H-indazole; With sodium hydride; In tetrahydrofuran; at 0 ℃;

With (2-trimethylethylsilylethoxy)methyl chloride; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

: 53857-57-1
5-bromo-1H-indazole

: 918440-14-9
5-bromo-3-iodo-1-[2-(trimethylsilanyl)ethoxymethyl]-1H-indazole

: 1012104-27-6
5-bromo-3-iodo-2-(2-trimethylsilanyl-ethoxymethyl)-1H-indazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydroxide; iodine / N,N-dimethyl-formamide / 20 °C

2.1: sodium hydride / tetrahydrofuran / 0 °C

2.2: 0 - 20 °C

With iodine; sodium hydride; potassium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide;