6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Base Information

Chemical Name:6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid
CAS No.:1101324-48-4
Molecular Formula:C13H7Cl2N3O3
Molecular Weight:324.123
Hs Code.:
Mol file:1101324-48-4.mol

Synonyms:6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Suppliers and Price of 6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Chemical Property:

PSA：87.46000
LogP:2.69460

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

There total 4 articles about 6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1101323-84-5
ethyl 6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylate

: 1101324-48-4
6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Guidance literature:: ethyl 6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylate; With sodium hydroxide; In 1,2-dimethoxyethane; at 20 ℃; for 3h;

With hydrogenchloride; In 1,2-dimethoxyethane; water; pH=3;

Reference yield:

: 37687-24-4
diethyl 1H-pyrazole-3,5-dicarboxylate

: 1101324-48-4
6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / acetone / 12 h / 20 °C

2.1: ammonium acetate; acetic acid / 12 h / Reflux

3.1: sodium hydroxide / 1,2-dimethoxyethane / 3 h / 20 °C

3.2: pH 3

With ammonium acetate; potassium carbonate; acetic acid; sodium hydroxide; In 1,2-dimethoxyethane; acetone;

Reference yield:

: 1101323-82-3
diethyl 1-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-pyrazole-3,5-dicarboxylate

: 1101324-48-4
6-(2,4-dichlorophenyl)-4-oxo-4,5-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: ammonium acetate; acetic acid / 12 h / Reflux

2.1: sodium hydroxide / 1,2-dimethoxyethane / 3 h / 20 °C

2.2: pH 3

With ammonium acetate; acetic acid; sodium hydroxide; In 1,2-dimethoxyethane;