(S)-3-Methylmorpholine

Base Information

Chemical Name:(S)-3-Methylmorpholine
CAS No.:350595-57-2
Molecular Formula:C5H11NO
Molecular Weight:101.148
Hs Code.:2934999090
European Community (EC) Number:635-416-7
DSSTox Substance ID:DTXSID00475799
Nikkaji Number:J3.462.318J
Wikidata:Q72493176
Mol file:350595-57-2.mol

Synonyms:(S)-3-Methylmorpholine;350595-57-2;(3S)-3-Methylmorpholine;(S)-3-Methyl-morpholine;(S)-3-methyl morpholine;3S-3-METHYLMORPHOLINE;MFCD03840369;Morpholine, 3-methyl-, (3S)-;3-Methyl-morpholine;3-(S)-methylmorpholine;SCHEMBL16926;DTXSID00475799;SFWWGMKXCYLZEG-YFKPBYRVSA-N;CS-M0392;(S)-3-methylmorpholine, AldrichCPR;AKOS006238789;AKOS015840072;GS-4044;AC-22432;AM803755;A6150;EN300-99039

Suppliers and Price of (S)-3-Methylmorpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Absolute Chiral
(S)-3-methylmorpholine 95%
500 mg
$ 298.00

ACHEMBLOCK
(S)-3-Methylmorpholine 95%
1G
$ 25.00

Activate Scientific
(S)-3-Methylmorpholine 98+% ee
1 g
$ 36.00

Activate Scientific
(S)-3-Methylmorpholine 98+% ee
25 g
$ 348.00

Activate Scientific
(S)-3-Methylmorpholine 98+% ee
5 g
$ 122.00

AK Scientific
(S)-3-Methylmorpholine
5g
$ 79.00

AK Scientific
(S)-3-Methylmorpholine
1g
$ 25.00

Alichem
(S)-3-Methylmorpholine
25g
$ 371.42

Ambeed
(S)-3-Methylmorpholine 97%
25g
$ 134.00

Ambeed
(S)-3-Methylmorpholine 97%
5g
$ 32.00

Total 78 raw suppliers

Chemical Property of (S)-3-Methylmorpholine

Chemical Property:

Vapor Pressure:7.14mmHg at 25°C
Refractive Index:1.409
Boiling Point:137.1 °C at 760 mmHg
PKA:9.03±0.40(Predicted)
Flash Point:41.3 °C
PSA：21.26000
Density:0.891 g/cm³
LogP:0.32350
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:101.084063974
Heavy Atom Count:7
Complexity:56

Purity/Quality:

99% ^*data from raw suppliers

(S)-3-methylmorpholine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1COCCN1
Isomeric SMILES:C[C@H]1COCCN1
Uses (3S)-3-Methylmorpholine is useful in preparation of morpholinopyrimidine derivatives as mTOR kinase inhibitors for the treatment of diseases mediated by mTOR kinase and/or one or more PI3K enzymes It is useful in preparation of morpholinopyrimidine derivatives as mTOR kinase inhibitors for the treatment of diseases mediated by mTOR kinase and/or one or more PI3K enzymes.

Technology Process of (S)-3-Methylmorpholine

There total 9 articles about (S)-3-Methylmorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 119844-66-5
(S)-5-methylmorpholin-3-one

: 350595-57-2
(S)-3-methylmorpholine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; Temperature; Inert atmosphere;

Reference yield:

: C₅H₉NO

: 350595-57-2
(S)-3-methylmorpholine

: 74572-04-6
(3R)-3-methylmorpholine

Guidance literature:: With [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); formic acid; silver trifluoromethanesulfonate; triethylamine; In N,N-dimethyl-formamide; at 23 ℃; for 16h; enantioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.joc.6b01884