2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile

Base Information

Chemical Name:2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile
CAS No.:24966-30-1
Molecular Formula:C11H9NO3
Molecular Weight:203.197
Hs Code.:
Mol file:24966-30-1.mol

Synonyms:2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile;a-Acetyl-1,3-benzodioxole-5-acetonitrile

Suppliers and Price of 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile 95%
10g
$ 422.00

Alichem
2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile
5g
$ 400.00

Acrotein
a-Acetyl-1,3-benzodioxole-5-acetonitrile 97%
0.5g
$ 74.43

Total 46 raw suppliers

Chemical Property of 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile

Chemical Property:

Boiling Point:307.4±42.0 °C(Predicted)
PSA：59.32000
Density:1.288±0.06 g/cm3(Predicted)
LogP:1.61148

Purity/Quality:

97% ^*data from raw suppliers

2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile

There total 5 articles about 2-(Benzo[d][1,3]dioxol-5-yl)-3-oxobutanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 141-78-6
ethyl acetate

: 4439-02-5
3,4-methylenedioxyphenylacetonitrile

: 24966-30-1
α-acetyl-α-(3',4'-methylenedioxyphenyl)acetonitrile

Guidance literature:: 3,4-methylenedioxyphenylacetonitrile; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 1h;

ethyl acetate; In tetrahydrofuran; mineral oil; at 0 - 70 ℃; for 4h;
DOI:10.1002/asia.201300595

Reference yield:

: 120-57-0,30024-74-9
piperonal

: 24966-30-1
α-acetyl-α-(3',4'-methylenedioxyphenyl)acetonitrile

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium tetrahydroborate / methanol / 0.5 h / 0 - 20 °C

2.1: hydrogenchloride / 1.5 h / 0 - 20 °C

3.1: tetrabutylammomium bromide / water; chloroform / 2 h / 20 - 60 °C

4.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C

4.2: 4 h / 0 - 70 °C

With hydrogenchloride; sodium tetrahydroborate; tetrabutylammomium bromide; sodium hydride; In tetrahydrofuran; methanol; chloroform; water; mineral oil; 4.2: |Michael Addition;
DOI:10.1002/asia.201300595

Reference yield:

: 495-76-1
piperonol

: 24966-30-1
α-acetyl-α-(3',4'-methylenedioxyphenyl)acetonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride / 1.5 h / 0 - 20 °C

2.1: tetrabutylammomium bromide / water; chloroform / 2 h / 20 - 60 °C

3.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C

3.2: 4 h / 0 - 70 °C

With hydrogenchloride; tetrabutylammomium bromide; sodium hydride; In tetrahydrofuran; chloroform; water; mineral oil; 3.2: |Michael Addition;
DOI:10.1002/asia.201300595