CarbaMic acid, N,N-di-2-propyn-1-yl-, 1,1-diMethylethyl ester

Base Information

• Chemical Name: CarbaMic acid, N,N-di-2-propyn-1-yl-, 1,1-diMethylethyl ester
• CAS No.: 262418-92-8
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Hs Code.: 2924297099
• Mol file: 262418-92-8.mol

Synonyms:CarbaMic acid, N,N-di-2-propyn-1-yl-, 1,1-diMethylethyl ester;tert-butyl di(prop-2-yn-1-yl)carbaMate;N-Boc-dipropargylamine;2-Methyl-2-propanyl di-2-propyn-1-ylcarbamate

Chemical Property of CarbaMic acid, N,N-di-2-propyn-1-yl-, 1,1-diMethylethyl ester

Chemical Property:

• PSA: 29.54000
• LogP: 1.48990

Purity/Quality:

≥95% ^*data from raw suppliers

tert-Butyldi(prop-2-yn-1-yl)carbamate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of CarbaMic acid, N,N-di-2-propyn-1-yl-, 1,1-diMethylethyl ester

There total 6 articles about CarbaMic acid, N,N-di-2-propyn-1-yl-, 1,1-diMethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-tert-Butoxycarbonyl-1-amino-3-propyne (92136-39-5) + propargyl bromide (106-96-7) → di-prop-2-ynyl-carbamic acid tert-butyl ester (262418-92-8)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃;

DOI:10.3390/molecules25040974

Reference yield: 100.0%

dipropargylamine (6921-28-4) + di-tert-butyl dicarbonate (24424-99-5) → di-prop-2-ynyl-carbamic acid tert-butyl ester (262418-92-8)

Guidance literature:

With triethylamine; In ethanol; at 20 ℃;

DOI:10.1016/j.bmc.2009.10.039

Reference yield: 77.0%

di-tert-butyl dicarbonate (24424-99-5) + propargyl bromide (106-96-7) + Propargylamine (2450-71-7) → di-prop-2-ynyl-carbamic acid tert-butyl ester (262418-92-8)

Guidance literature:

di-tert-butyl dicarbonate; Propargylamine; In dichloromethane;

propargyl bromide; With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1002/chem.201803902

upstream raw materials:

N-tert-Butoxycarbonyl-1-amino-3-propyne

propargyl bromide

di-tert-butyl dicarbonate

dipropargylamine

Downstream raw materials:

tert-butyl 5-(hydroxymethyl)-1,3-dihydro-2H-isoindole-2-carboxylate

5-(4-methyl-piperazin-1-ylmethyl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester p-toluenesulphonic acid salt

tert-butyl 5-(2-hydroxyethyl)isoindoline-2-carboxylate

C₂₀H₂₃NO₂