Avanbulin

Base Information

Chemical Name:Avanbulin
CAS No.:798577-91-0
Molecular Formula:C₂₀H₁₇N₇O₂
Molecular Weight:387.401
Hs Code.:
UNII:Y7KSX9YI58
Wikidata:Q27453216
NCI Thesaurus Code:C169796
ChEMBL ID:CHEMBL3422109

Synonyms:BAL27862

Suppliers and Price of Avanbulin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of Avanbulin

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:387.14437281
Heavy Atom Count:29
Complexity:615

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N=C(N2CC(=O)C3=CC=C(C=C3)N)C4=NON=C4NCCC#N

Technology Process of Avanbulin

There total 9 articles about Avanbulin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 332026-86-5
3-amino-4-(1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazole

: 798577-91-0
3-(4-{1-[2-(4-amino-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-furazan-3-ylamino)-propionitrile

Guidance literature:: Multi-step reaction with 3 steps

1: sodium methylate / pyridine; methanol / 20 °C / Cooling with ice

2: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C

3: hydrogen / palladium 10% on activated carbon / ethyl acetate; methanol / 3 h / 20 °C / 760.05 Torr

With hydrogen; sodium methylate; potassium carbonate; palladium 10% on activated carbon; In pyridine; methanol; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 1263384-50-4
[4-(2-{2-[4-(2-cyano-ethylamino)furazan-3-yl]benzoimidazol-1-yl}acetyl)phenyl]carbamic acid benzyl ester

: 798577-91-0
3-(4-{1-[2-(4-amino-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-furazan-3-ylamino)-propionitrile

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; ethyl acetate; at 20 ℃; for 3h; under 760.051 Torr;

Reference yield:

: 157014-41-0
4-((carbobenzyloxy)amino)phenacyl bromide

: 798577-91-0
3-(4-{1-[2-(4-amino-phenyl)-2-oxo-ethyl]-1H-benzoimidazol-2-yl}-furazan-3-ylamino)-propionitrile

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 20 °C

2: hydrogen / palladium 10% on activated carbon / ethyl acetate; methanol / 3 h / 20 °C / 760.05 Torr

With hydrogen; potassium carbonate; palladium 10% on activated carbon; In methanol; ethyl acetate; N,N-dimethyl-formamide;