Benzyl (4-(2-bromoacetyl)phenyl)carbamate

Base Information

Chemical Name:Benzyl (4-(2-bromoacetyl)phenyl)carbamate
CAS No.:157014-41-0
Molecular Formula:C16H14 Br N O3
Molecular Weight:348.196
Hs Code.:2924299090
DSSTox Substance ID:DTXSID40597085
Wikidata:Q72451290
Mol file:157014-41-0.mol

Synonyms:Benzyl (4-(2-bromoacetyl)phenyl)carbamate;157014-41-0;N-Cbz-4-(2-bromo-acetyl)-aniline;benzyl N-[4-(2-bromoacetyl)phenyl]carbamate;MFCD05663954;Carbamic acid, [4-(bromoacetyl)phenyl]-, phenylmethyl ester (9CI);Benzyl(4-(2-bromoacetyl)phenyl)carbamate;SCHEMBL1160190;DTXSID40597085;SGOOUOYLZRYRQG-UHFFFAOYSA-N;AMY32179;ZINC02547897;AKOS015999522;AB22050;Benzyl [4-(bromoacetyl)phenyl]carbamate;benzyl 4-(2-bromoacetyl)phenylcarbamate;DS-17839;SY105415;1-[4-(Cbz-amino)phenyl]-2-bromoethanone;DB-064156;CS-0187314;C72971;A883527;[4-(2-bromo-acetyl)-phenyl]-carbamic acid benzyl ester

Suppliers and Price of Benzyl (4-(2-bromoacetyl)phenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Benzyl (4-(2-bromoacetyl)phenyl)carbamate 95+%
5g
$ 1512.00

Matrix Scientific
Benzyl (4-(2-bromoacetyl)phenyl)carbamate 95+%
250mg
$ 246.00

Matrix Scientific
Benzyl (4-(2-bromoacetyl)phenyl)carbamate 95+%
1g
$ 538.00

J&W Pharmlab
N-Cbz-4-(2-bromo-acetyl)-aniline 97%
5g
$ 285.00

J&W Pharmlab
N-Cbz-4-(2-bromo-acetyl)-aniline 97%
25g
$ 998.00

J&W Pharmlab
N-Cbz-4-(2-bromo-acetyl)-aniline 97%
1g
$ 88.00

J&W Pharmlab
N-Cbz-4-(2-bromo-acetyl)-aniline 97%
500mg
$ 78.00

J&W Pharmlab
N-Cbz-4-(2-bromo-acetyl)-aniline 97%
250mg
$ 68.00

Crysdot
Benzyl(4-(2-bromoacetyl)phenyl)carbamate 95+%
5g
$ 327.00

Crysdot
Benzyl(4-(2-bromoacetyl)phenyl)carbamate 95+%
10g
$ 614.00

Total 25 raw suppliers

Chemical Property of Benzyl (4-(2-bromoacetyl)phenyl)carbamate

Chemical Property:

PSA：55.40000
Density:1.486
LogP:4.08590
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:347.01571
Heavy Atom Count:21
Complexity:347

Purity/Quality:

97% ^*data from raw suppliers

Benzyl (4-(2-bromoacetyl)phenyl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NC2=CC=C(C=C2)C(=O)CBr

Technology Process of Benzyl (4-(2-bromoacetyl)phenyl)carbamate

There total 4 articles about Benzyl (4-(2-bromoacetyl)phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 72531-10-3
4-<<(benzyloxy)carbonyl>amino>acetophenone

: 157014-41-0
4-((carbobenzyloxy)amino)phenacyl bromide

Guidance literature:: With aluminium trichloride; bromine; In tetrahydrofuran; at 0 ℃; for 40h;
DOI:10.1021/ja9635589

Reference yield:

: 99-92-3
p-aminobenzophenone

: 157014-41-0
4-((carbobenzyloxy)amino)phenacyl bromide

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / NaOH / dioxane; H₂O / 2.5 h / 0 - 25 °C

2: 93 percent / Br₂; AlCl₃ / tetrahydrofuran / 40 h / 0 °C

With sodium hydroxide; aluminium trichloride; bromine; In tetrahydrofuran; 1,4-dioxane; water; 1: alkoxycarbonylation / 2: Bromination;
DOI:10.1021/ja9635589

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 157014-41-0
4-((carbobenzyloxy)amino)phenacyl bromide

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / NaOH / dioxane; H₂O / 2.5 h / 0 - 25 °C

2: 93 percent / Br₂; AlCl₃ / tetrahydrofuran / 40 h / 0 °C

With sodium hydroxide; aluminium trichloride; bromine; In tetrahydrofuran; 1,4-dioxane; water; 1: alkoxycarbonylation / 2: Bromination;
DOI:10.1021/ja9635589