157014-41-0

Basic information

• Product Name: N-CBZ-4-(2-BROMO-ACETYL)-ANILINE
• Synonyms: N-CBZ-4-(2-BROMO-ACETYL)-ANILINE;[4-(Bromoacetyl)phenyl]carbamic acid phenylmethyl ester;Benzyl (4-(2-broMoacetyl)phenyl)carbaMate;CarbaMic acid,[4-(broMoacetyl)phenyl]-, phenylMethyl ester (9CI)
• CAS NO: 157014-41-0
• Molecular Formula: C₁₆H₁₄BrNO₃
• Molecular Weight: 348.19
• Mol File: 157014-41-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.486
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: N-CBZ-4-(2-BROMO-ACETYL)-ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-CBZ-4-(2-BROMO-ACETYL)-ANILINE(157014-41-0)
• EPA Substance Registry System: N-CBZ-4-(2-BROMO-ACETYL)-ANILINE(157014-41-0)

Safety Data

• Hazardous Substances Data: 157014-41-0(Hazardous Substances Data)

Usage

General Description

N-CBZ-4-(2-Bromo-acetyl)-aniline is a chemical compound that belongs to the class of anilines. It features a carbobenzyloxy (CBZ) protecting group attached to the nitrogen atom, as well as a 2-bromo-acetyl group attached to the benzene ring. N-CBZ-4-(2-BROMO-ACETYL)-ANILINE has a wide range of applications in the fields of organic synthesis and pharmaceutical research. It can be used as an intermediate for the synthesis of various organic compounds, including pharmaceutical drugs and agrochemicals. Its unique structure and reactivity make it a versatile building block for the development of new chemical entities with potential biological activities. Additionally, it can also be employed as a reagent in the preparation of complex molecules with carefully designed structures and properties. Overall, N-CBZ-4-(2-Bromo-acetyl)-aniline is a valuable chemical tool for the synthesis and modification of organic molecules with diverse applications.

Upstream product

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Downstream Products

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• 1263384-51-5 (S)-{5-benzyloxycarbonylamino-5-[4-(2-{2-[4-(2-cyanoethylamino)furazan-3-yl]benzoimidazol-1-yl}acetyl)phenylcarbamoyl]pentyl}carbamic acid benzyl ester 
• 1263384-40-2 N'-[4-(2-{2-[4-(2-cyano-ethylamino)furazan-3-yl]benzoimidazol-1-yl}acetyl)phenyl]-N,N-dimethyl-formamidine 
• 1263384-41-3 [4-(2-{2-[4-(2-cyano-ethylamino)furazan-3-yl]benzoimidazol-1-yl}acetyl)phenyl]sulfamic acid sodium salt 
• 1263384-50-4 [4-(2-{2-[4-(2-cyano-ethylamino)furazan-3-yl]benzoimidazol-1-yl}acetyl)phenyl]carbamic acid benzyl ester 
• 1263384-58-2 [4-(2-{2-[4-(2-benzyloxycarbonylamino-acetylamino)furazan-3-yl]benzoimidazol-1-yl}acetyl)phenyl]carbamic acid benzyl ester 
• 1443114-21-3 benzyl (4-(2-(2-(3-benzamidopyrazin-2-yl)-1H-benzo[d]imidazol-1-yl)acetyl)phenyl)carbamate 
• 1443114-11-1 benzyl (4-(2-(2-(4-(2-fluorobenzamido)-1,2,5-oxadiazol-3-yl)-1H-benzo[d]imidazol-1-yl)acetyl)phenyl)carbamate 
• 157012-55-0 5,6-Bis(4-methoxyphenyl)-7-methyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine 
• 157012-68-5 6-(2-methoxyphenyl)-7-methyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine 
• 157012-65-2 6-(2,5-dimethoxyphenyl)-7-methyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine 

Relevant articles and documents

FURAZANOBENZIMIDAZOLES AS PRODRUGS TO TREAT NEOPLASTIC OR AUTOIMMUNE DISEASES

A compound of formula (II) wherein (a) represents a divalent benzene residue which is unsubstituted or substituted by one or two additional substituents independently selected from lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, acyloxy-lower alkyl, phenyl, hydroxy, lower alkoxy, hydroxy-lower alkoxy, lower alkoxy-lower alkoxy, phenyl-lower alkoxy, lower alkylcarbonyloxy, amino, mono(lower alkyl)amino, di(lower alkyl)amino, mono(lower alkenyl)amino, di(lower alkenyl)amino, lower alkoxycarbonylamino, lower alkylcarbonylamino, substituted amino wherein the two substituents on nitrogen form together with the nitrogen heterocyclyl, lower alkylcarbonyl, carboxy, lower 15 alkoxycarbonyl, cyano, halogen, and nitro; or wherein two adjacent substituents can be methylenedioxy; or a divalent pyridine residue (Z = N) which is unsubstituted or substituted additionally by lower alkyl, lower alkoxy, lower alkoxy-lower alkoxy,amino, optionally substituted by one or two substituents selected from lower alkyl, lower alkenyl and alkylcarbonyl, halo-20 lower alkyl, lower alkoxy-lower alkyl, or halogen; R1 represents hydrogen, lower alkylcarbonyl, hydroxy-lower alkylor cyano-loweralkyl; and R2 represents a group selected from: (b), (c) and (d); or pharmaceutically acceptable salts thereof.