1-(3-broMophenyl)-3-(2,2,2-trifluoroethyl)urea

Base Information

Chemical Name:1-(3-broMophenyl)-3-(2,2,2-trifluoroethyl)urea
CAS No.:1036990-21-2
Molecular Formula:C9H8BrF3N2O
Molecular Weight:297.075
Hs Code.:
Mol file:1036990-21-2.mol

Synonyms:1-(3-broMophenyl)-3-(2,2,2-trifluoroethyl)urea;N-(3-Bromophenyl)-N'-(2,2,2-trifluoroethyl)-urea

Suppliers and Price of 1-(3-broMophenyl)-3-(2,2,2-trifluoroethyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-(3-Bromophenyl)-3-(2,2,2-trifluoroethyl)urea 95%
5g
$ 1403.00

Crysdot
1-(3-Bromophenyl)-3-(2,2,2-trifluoroethyl)urea 95+%
1g
$ 402.00

Alichem
1-(3-Bromophenyl)-3-(2,2,2-trifluoroethyl)urea
1g
$ 400.00

A1 Biochem Labs
1-(3-Bromophenyl)-3-(2,2,2-trifluoroethyl)urea 95%
5 g
$ 850.00

Total 5 raw suppliers

Chemical Property of 1-(3-broMophenyl)-3-(2,2,2-trifluoroethyl)urea

Chemical Property:

PSA：44.62000
LogP:3.41030
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Bromophenyl)-3-(2,2,2-trifluoroethyl)urea 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(3-broMophenyl)-3-(2,2,2-trifluoroethyl)urea

There total 1 articles about 1-(3-broMophenyl)-3-(2,2,2-trifluoroethyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 753-90-2
trifluoroethylamine

: 23138-55-8
3-Bromophenyl isocyanate

: 1036990-21-2
1-(3-bromo-phenyl)-3-(2,2,2-trifluoro-ethyl)-urea

Guidance literature:: In dichloromethane; for 2h;
DOI:10.1002/cmdc.201900359

Reference yield:

: 1036990-21-2
1-(3-bromo-phenyl)-3-(2,2,2-trifluoro-ethyl)-urea

: 73183-34-3
bis(pinacol)diborane

: 874299-21-5
1-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-3-(2,2,2-trifluoro-ethyl)-urea

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 100 ℃; Inert atmosphere;

Reference yield:

: 1036990-21-2
1-(3-bromo-phenyl)-3-(2,2,2-trifluoro-ethyl)-urea

: 1251899-88-3
1-[3-(7-{(E)-1-2-hydroxyethoxyiminoethyl}imidazo[1,2-a]pyridin-3-yl)phenyl]-3-(2,2,2-trifluoroethyl)urea

Guidance literature:: Multi-step reaction with 4 steps

1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 100 °C / Inert atmosphere

2: potassium phosphate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane; water / 5 h / 80 °C / Inert atmosphere

3: hydroxylamine hydrochloride; pyridine / ethanol

4: caesium carbonate / dimethyl sulfoxide / 12 h / 20 °C

With pyridine; potassium phosphate; hydroxylamine hydrochloride; potassium acetate; caesium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; ethanol; water; dimethyl sulfoxide;