N-Propionyl-(2S)-bornane-10,2-sultaM

Base Information

• Chemical Name: N-Propionyl-(2S)-bornane-10,2-sultaM
• CAS No.: 195877-80-6
• Molecular Formula: C13H21NO3S
• Molecular Weight: 271.37574
• Mol file: 195877-80-6.mol

Synonyms:1-((1S,5S,7R)-10,10-Dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-propan-1-one;

Chemical Property of N-Propionyl-(2S)-bornane-10,2-sultaM

Chemical Property:

• Melting Point: 149.9 - 150.7 °C (methanol)
• PSA: 62.83000
• LogP: 2.78200

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Propionyl-(2S)-bornane-10,2-sultaM

There total 1 articles about N-Propionyl-(2S)-bornane-10,2-sultaM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

propionyl chloride (79-03-8) + Bornane<10,2>sultam (195877-76-0,124224-04-0) → N-propionyl-2(S)-bornane-2,10-sultam (195877-80-6)

Guidance literature:

Bornane<10,2>sultam; With sodium hydride; In tetrahydrofuran; toluene; at 20 ℃; for 1h;

propionyl chloride; In tetrahydrofuran; toluene; for 16h;

DOI:10.1021/jm9811209

Reference yield: 53.0%

2-nitrophenylmethyl bromide (3958-60-9) + N-propionyl-2(S)-bornane-2,10-sultam (195877-80-6) → N-[2(R)-methyl-3-(2-nitrophenyl)propionyl]-2(S)-bornane-2,10-sultam

Guidance literature:

N-propionyl-2(S)-bornane-2,10-sultam; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;

2-nitrophenylmethyl bromide; In tetrahydrofuran; at -78 - 20 ℃; for 19.5h;

DOI:10.1021/jm9811209

upstream raw materials:

propionyl chloride

Bornane<10,2>sultam

Refernces