1-Chloro-6-methoxyphthalazine

Base Information

Chemical Name:1-Chloro-6-methoxyphthalazine
CAS No.:256443-70-6
Molecular Formula:C9H7ClN2O
Molecular Weight:194.61768
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30593314
Wikidata:Q82487772
Mol file:256443-70-6.mol

Synonyms:1-CHLORO-6-METHOXYPHTHALAZINE;256443-70-6;1-CHLORO-6-METHOXY-PHTHALAZINE;SCHEMBL3373707;DTXSID30593314;XXFKOPXFBGNEGQ-UHFFFAOYSA-N;AKOS006330510;AB50536;DB-259501;A919486

Suppliers and Price of 1-Chloro-6-methoxyphthalazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Chloro-6-methoxyphthalazine 95+%
1g
$ 762.00

Chemenu
1-Chloro-6-methoxy-phthalazine 95%
1g
$ 720.00

American Custom Chemicals Corporation
1-CHLORO-6-METHOXY-PHTHALAZINE 95.00%
5MG
$ 504.34

Alichem
1-Chloro-6-methoxyphthalazine
1g
$ 620.00

Total 6 raw suppliers

Chemical Property of 1-Chloro-6-methoxyphthalazine

Chemical Property:

PSA：35.01000
LogP:2.29180
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:194.0246905
Heavy Atom Count:13
Complexity:179

Purity/Quality:

97% ^*data from raw suppliers

1-Chloro-6-methoxyphthalazine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=CN=NC(=C2C=C1)Cl

Technology Process of 1-Chloro-6-methoxyphthalazine

There total 4 articles about 1-Chloro-6-methoxyphthalazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.3%

: 60889-21-6
6-methoxyphthalazin-1-(2H)-one

: 256443-70-6
1-chloro-6-methoxyphthalazine

Guidance literature:: With trichlorophosphate; In acetonitrile; for 3h; Heating;
DOI:10.1016/S0960-894X(01)00668-0

Reference yield:

: 53416-46-9
2-(4-methoxyphenyl)-4,4-dimethyl-2-oxazoline

: 256443-70-6
1-chloro-6-methoxyphthalazine

Guidance literature:: Multi-step reaction with 4 steps

1.1: BuLi / diethyl ether / 4 h / 0 °C

1.2: 84 percent / diethyl ether / 8 h / 20 °C

2.1: 90 percent / 50 percent aq. H₂SO₄ / ethanol / 20 h / Heating

3.1: 82 percent / hydrazine hydrate; AcOH / 4 h / 80 °C

4.1: 98 percent / POCl₃ / acetonitrile / 3 h / Heating

With n-butyllithium; sulfuric acid; hydrazine hydrate; acetic acid; trichlorophosphate; In diethyl ether; ethanol; acetonitrile;
DOI:10.1016/S0960-894X(01)00668-0

Reference yield:

: 70097-50-6
3-hydroxy-5-methoxyisobenzofuran-1(3H)-one

: 256443-70-6
1-chloro-6-methoxyphthalazine

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / hydrazine hydrate; AcOH / 4 h / 80 °C

2: 98 percent / POCl₃ / acetonitrile / 3 h / Heating

With hydrazine hydrate; acetic acid; trichlorophosphate; In acetonitrile;
DOI:10.1016/S0960-894X(01)00668-0