6-Methoxy-2H-phthalazin-1-one

Base Information

• Chemical Name: 6-Methoxy-2H-phthalazin-1-one
• CAS No.: 60889-21-6
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.175
• European Community (EC) Number: 874-754-1
• Nikkaji Number: J1.667.001D

Synonyms:6-Methoxyphthalazin-1-ol;60889-21-6;6-Methoxy-2H-phthalazin-1-one;SCHEMBL1009542;SCHEMBL25231831;ORPXLLBGLYKJDO-UHFFFAOYSA-N;AKOS006290819;6-methoxy-1,2-dihydrophthalazin-1-one;EN300-339552

Chemical Property of 6-Methoxy-2H-phthalazin-1-one

Chemical Property:

• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 176.058577502
• Heavy Atom Count: 13
• Complexity: 240

Purity/Quality:

6-Methoxy-2H-phthalazin-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC2=C(C=C1)C(=O)NN=C2

Technology Process of 6-Methoxy-2H-phthalazin-1-one

There total 10 articles about 6-Methoxy-2H-phthalazin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

3-hydroxy-5-methoxyisobenzofuran-1(3H)-one (70097-50-6) → 6-methoxyphthalazin-1-(2H)-one (60889-21-6)

Guidance literature:

With hydrazine hydrate; acetic acid; at 80 ℃; for 4h;

DOI:10.1016/S0960-894X(01)00668-0

Reference yield: 73.4%

2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-5-methoxy-benzaldehyde (56446-25-4) → 6-methoxyphthalazin-1-(2H)-one (60889-21-6)

Guidance literature:

With concentrated H₂SO₄; hydrazine hydrate; In ethanol; dichloromethane; water; acetic acid;

Reference yield: 55.0%

2-formyl-4-methoxybenzoic acid (60373-42-4) → 6-methoxyphthalazin-1-(2H)-one (60889-21-6)

Guidance literature:

With hydrazine hydrate; In ethanol; at 85 ℃; for 1h;

upstream raw materials:

3-hydroxy-5-methoxyisobenzofuran-1(3H)-one

2-(4-methoxyphenyl)-4,4-dimethyl-2-oxazoline

2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-5-methoxy-benzaldehyde

dimethyl 4-methoxyphtalate

Downstream raw materials:

1-chloro-6-methoxyphthalazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 60889-21-6 6-methoxyphthalazin-1-(2H)-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send