6-Chloro-2-phenyl-4-pyrimidinyl4-methoxybenzylether

Base Information

• Chemical Name: 6-Chloro-2-phenyl-4-pyrimidinyl4-methoxybenzylether
• CAS No.: 1044559-74-1
• Molecular Formula: C18H15ClN2O2
• Molecular Weight: 326.782
• Mol file: 1044559-74-1.mol

Synonyms:6-Chloro-2-phenyl-4-pyrimidinyl4-methoxybenzylether

Chemical Property of 6-Chloro-2-phenyl-4-pyrimidinyl4-methoxybenzylether

Chemical Property:

• Melting Point: 94-96°
• PSA: 44.24000
• LogP: 4.38460

Purity/Quality:

97% ^*data from raw suppliers

6-Chloro-2-phenyl-4-pyrimidinyl4-MethoxybenzylEther ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Chloro-2-phenyl-4-pyrimidinyl4-methoxybenzylether

There total 1 articles about 6-Chloro-2-phenyl-4-pyrimidinyl4-methoxybenzylether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

fenclorim (3740-92-9) + 4-Methoxybenzyl alcohol (105-13-5) → 4-chloro-6-(4-methoxybenzyloxy)-2-phenylpyrimidine (1044559-74-1)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 ℃; for 1.5h;

Reference yield: 64.0%

4-chloro-6-(4-methoxybenzyloxy)-2-phenylpyrimidine (1044559-74-1) + sodium methylate (124-41-4) → 4-methoxy-6-(4-methoxy-benzyloxy)-2-phenyl-pyrimidine (1044559-77-4)

Guidance literature:

In methanol; at 0 ℃; for 8h; Heating / reflux;

upstream raw materials:

fenclorim

4-Methoxybenzyl alcohol

Downstream raw materials:

4-methoxy-6-(4-methoxy-benzyloxy)-2-phenyl-pyrimidine

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