Technology Process of Pyridarone
There total 9 articles about Pyridarone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluorormethanesulfonic acid;
In
1,4-dioxane;
at 120 ℃;
for 12h;
DOI:10.1039/c3ob42039f
- Guidance literature:
-
4-pyridinecarboxylic acid, methyl ester; ortho-bromophenylacetic acid;
With
sodium hexamethyldisilazane;
In
tetrahydrofuran; N,N-dimethyl-formamide;
at -10 ℃;
for 3.5h;
Inert atmosphere;
With
potassium dihydrogenphosphate; copper(l) iodide; potassium phosphate tribasic heptahydrate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
at 110 ℃;
for 6h;
Inert atmosphere;
DOI:10.1039/c2gc16457d
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere
2: trifluorormethanesulfonic acid / 1,4-dioxane / 12 h / 120 °C
With
trifluorormethanesulfonic acid; potassium carbonate;
In
1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1039/c3ob42039f
