(2S)-2-amino-2-(4-tert-butylphenyl)ethanol

Base Information

Chemical Name:(2S)-2-amino-2-(4-tert-butylphenyl)ethanol
CAS No.:191109-50-9
Molecular Formula:C12H19NO
Molecular Weight:193.28536
Hs Code.:2922199090
European Community (EC) Number:693-838-7
DSSTox Substance ID:DTXSID60584795
Wikidata:Q76511218
Mol file:191109-50-9.mol

Synonyms:191109-50-9;(2S)-2-amino-2-(4-tert-butylphenyl)ethanol;(S)-2-Amino-2-(4-(tert-butyl)phenyl)ethanol;(S)-(+)-2-Amino-2-(4-tert-butylphenyl)ethanol;(2S)-2-Amino-2-(4-tert-butylphenyl)ethan-1-ol;(S)-2-amino-2-(4-(tert-butyl)phenyl)ethan-1-ol;Benzeneethanol, beta-amino-4-(1,1-dimethylethyl)-, (betaS)-;DTXSID60584795;AM9219;AKOS015928274;AS-79341;CS-0272931;Y12025;EN300-1838032;(2S)-2-amino-2-[4-(tert-butyl)phenyl]ethan-1-ol;(S)-2-AMINO-2-(4-TERT-BUTYLPHENYL)ETHANOL;J-012348;(S)-(+)-2-Amino-2-(4-tert-butylphenyl)ethanol, 97%;Benzeneethanol, ss-amino-4-(1,1-dimethylethyl)-, (ssS)-

Suppliers and Price of (2S)-2-amino-2-(4-tert-butylphenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(S)-(+)-2-Amino-2-(4-tert-butylphenyl)ethanol 97%
1g
$ 1080.00

Sigma-Aldrich
(S)-(+)-2-Amino-2-(4-tert-butylphenyl)ethanol 97%
250mg
$ 380.00

American Custom Chemicals Corporation
(S)-(+)-2-AMINO-2-(4-TERT-BUTYLPHENYL)ETHANOL 97.00%
1G
$ 1707.55

American Custom Chemicals Corporation
(S)-(+)-2-AMINO-2-(4-TERT-BUTYLPHENYL)ETHANOL 97.00%
250MG
$ 946.55

Total 13 raw suppliers

Chemical Property of (2S)-2-amino-2-(4-tert-butylphenyl)ethanol

Chemical Property:

Melting Point:115-119 °C
PSA：46.25000
LogP:2.67650
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:193.146664230
Heavy Atom Count:14
Complexity:166

Purity/Quality:

99%, ^*data from raw suppliers

(S)-(+)-2-Amino-2-(4-tert-butylphenyl)ethanol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 37/38-41-43
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)C(CO)N
Isomeric SMILES:CC(C)(C)C1=CC=C(C=C1)[C@@H](CO)N

Technology Process of (2S)-2-amino-2-(4-tert-butylphenyl)ethanol

There total 5 articles about (2S)-2-amino-2-(4-tert-butylphenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1746-23-2,26009-55-2
4-tert-Butylstyrene

: 191109-50-9
(S)-(+)-2-amino-2-(p-tert-butylphenyl)ethanol

Guidance literature:: Multi-step reaction with 4 steps

1: K₃Fe(CN)6, K₂CO₃, (DHQD)2-PHAL, K₂OsO₄(H₂O)2

2: NaOH

3: NaN₃, H₂O / dimethylformamide

4: LiAlH₄ / tetrahydrofuran / Ambient temperature

With sodium hydroxide; potassium osmate(VI); lithium aluminium tetrahydride; sodium azide; water; potassium carbonate; 1,4-bis(9-O-dihydroquinidine)phthalazine; potassium hexacyanoferrate(III); In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(97)00322-0

Reference yield:

: 191109-41-8
(R)-1-(4-(tert-butyl)phenyl)ethane-1,2-diol

: 191109-50-9
(S)-(+)-2-amino-2-(p-tert-butylphenyl)ethanol

Guidance literature:: Multi-step reaction with 3 steps

1: NaOH

2: NaN₃, H₂O / dimethylformamide

3: LiAlH₄ / tetrahydrofuran / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; sodium azide; water; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(97)00322-0

Reference yield:

: 191109-42-9
(R)-4-(p-tert-butylphenyl)-1,3-dioxolane-2-one

: 191109-50-9
(S)-(+)-2-amino-2-(p-tert-butylphenyl)ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: NaN₃, H₂O / dimethylformamide

2: LiAlH₄ / tetrahydrofuran / Ambient temperature

With lithium aluminium tetrahydride; sodium azide; water; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(97)00322-0