191109-42-9

Upstream product

• 616-38-6 carbonic acid dimethyl ester 
• 191109-41-8 (R)-1-(4-(tert-butyl)phenyl)ethane-1,2-diol 
• 1746-23-2 4-tert-Butylstyrene 

Downstream Products

• 191109-45-2 (S)-2-azido-2-(p-tert-butylphenyl)ethanol 
• 191109-55-4 2-(Bis-{[(S)-1-(4-tert-butyl-phenyl)-2-hydroxy-ethylcarbamoyl]-methyl}-amino)-N-[(S)-1-(4-tert-butyl-phenyl)-2-hydroxy-ethyl]-acetamide 
• 191109-50-9 (S)-(+)-2-amino-2-(p-tert-butylphenyl)ethanol 

Relevant academic research and scientific papers

Enantioselective allylic oxidation of cycloalkenes by using Cu(II)-tris(oxazoline) complex as a catalyst

Optically active copper(II)-tris(oxazoline) complex that was synthesized as a model compound of the active site of non-heme oxygenase, was found to catalyze allylic oxidation of cycloalkenes to give the corresponding 2-cycloalkenyl benzoates with moderate to excellent enantioselectivity (up to 93% ee) under die Kharash-Sosnovsky reaction conditions.

Asymmetric Allylic C-H Alkylation via Palladium(II)/ cis-ArSOX Catalysis

We report the development of Pd(II)/cis-aryl sulfoxide-oxazoline (cis-ArSOX) catalysts for asymmetric C-H alkylation of terminal olefins with a variety of synthetically versatile nucleophiles. The modular, tunable, and oxidatively stable ArSOX scaffold is key to the unprecedented broad scope and high enantioselectivity (37 examples, avg. > 90% ee). Pd(II)/cis-ArSOX is unique in its ability to effect high reactivity and catalyst-controlled diastereoselectivity on the alkylation of aliphatic olefins. We anticipate that this new chiral ligand class will find use in other transition metal catalyzed processes that operate under oxidative conditions.