191109-41-8

Basic information

• Product Name: (R)-1-(4-(tert-butyl)phenyl)ethane-1,2-diol
• Synonyms: (R)-1-(4-(tert-butyl)phenyl)ethane-1,2-diol
• CAS NO: 191109-41-8
• Molecular Weight: 194.274
• Mol File: 191109-41-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (R)-1-(4-(tert-butyl)phenyl)ethane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(4-(tert-butyl)phenyl)ethane-1,2-diol(191109-41-8)
• EPA Substance Registry System: (R)-1-(4-(tert-butyl)phenyl)ethane-1,2-diol(191109-41-8)

Safety Data

• Hazardous Substances Data: 191109-41-8(Hazardous Substances Data)

Upstream product

• 1746-23-2 4-tert-Butylstyrene 
• 939-97-9 4-tert-Butylbenzaldehyde 

Downstream Products

• 191109-55-4 2-(Bis-{[(S)-1-(4-tert-butyl-phenyl)-2-hydroxy-ethylcarbamoyl]-methyl}-amino)-N-[(S)-1-(4-tert-butyl-phenyl)-2-hydroxy-ethyl]-acetamide 
• 191109-45-2 (S)-2-azido-2-(p-tert-butylphenyl)ethanol 
• 191109-50-9 (S)-(+)-2-amino-2-(p-tert-butylphenyl)ethanol 
• 34386-42-0 (S)-1-(4-tert-butylphenyl)ethanol 
• 191109-42-9 (R)-4-(p-tert-butylphenyl)-1,3-dioxolane-2-one 

Relevant articles and documents

Asymmetric Allylic C-H Alkylation via Palladium(II)/ cis-ArSOX Catalysis

We report the development of Pd(II)/cis-aryl sulfoxide-oxazoline (cis-ArSOX) catalysts for asymmetric C-H alkylation of terminal olefins with a variety of synthetically versatile nucleophiles. The modular, tunable, and oxidatively stable ArSOX scaffold is key to the unprecedented broad scope and high enantioselectivity (37 examples, avg. > 90% ee). Pd(II)/cis-ArSOX is unique in its ability to effect high reactivity and catalyst-controlled diastereoselectivity on the alkylation of aliphatic olefins. We anticipate that this new chiral ligand class will find use in other transition metal catalyzed processes that operate under oxidative conditions.

Structurally Defined Molecular Hypervalent Iodine Catalysts for Intermolecular Enantioselective Reactions

Molecular structures of the most prominent chiral non-racemic hypervalent iodine(III) reagents to date have been elucidated for the first time. The formation of a chirally induced supramolecular scaffold based on a selective hydrogen-bonding arrangement provides an explanation for the consistently high asymmetric induction with these reagents. As an exploratory example, their scope as chiral catalysts was extended to the enantioselective dioxygenation of alkenes. A series of terminal styrenes are converted into the corresponding vicinal diacetoxylation products under mild conditions and provide the proof of principle for a truly intermolecular asymmetric alkene oxidation under iodine(I/III) catalysis.

Enantioselective allylic oxidation of cycloalkenes by using Cu(II)-tris(oxazoline) complex as a catalyst

Optically active copper(II)-tris(oxazoline) complex that was synthesized as a model compound of the active site of non-heme oxygenase, was found to catalyze allylic oxidation of cycloalkenes to give the corresponding 2-cycloalkenyl benzoates with moderate to excellent enantioselectivity (up to 93% ee) under die Kharash-Sosnovsky reaction conditions.