1H-Thieno[3,4-d]iMidazole-4-pentanoic acid, 1-[bis(4-Methoxyphenyl)phenylMethyl]hexahydro-2-oxo-, [3aS-(3aa,4b,6aa)]-

Base Information

Chemical Name:1H-Thieno[3,4-d]iMidazole-4-pentanoic acid, 1-[bis(4-Methoxyphenyl)phenylMethyl]hexahydro-2-oxo-, [3aS-(3aa,4b,6aa)]-
CAS No.:144095-63-6
Molecular Formula:C31H34N2O5S
Molecular Weight:546.67706
Hs Code.:
Mol file:144095-63-6.mol

Synonyms:1H-Thieno[3,4-d]iMidazole-4-pentanoic acid, 1-[bis(4-Methoxyphenyl)phenylMethyl]hexahydro-2-oxo-, [3aS-(3aa,4b,6aa)]-;1'N-(4,4'-DiMethoxytrityl) Biotin

Suppliers and Price of 1H-Thieno[3,4-d]iMidazole-4-pentanoic acid, 1-[bis(4-Methoxyphenyl)phenylMethyl]hexahydro-2-oxo-, [3aS-(3aa,4b,6aa)]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1''N-(4,4''-Dimethoxytrityl)Biotin
100 mg
$ 160.00

Sigma-Aldrich
1-N-(4,4′-Dimethoxytrityl)-D-(+)-biotin >95%
1g
$ 305.00

Sigma-Aldrich
1-N-(4,4′-Dimethoxytrityl)-D-(+)-biotin >95%
5g
$ 1180.00

Medical Isotopes, Inc.
1??N-(4,4??-Dimethoxytrityl)Biotin
25 mg
$ 800.00

American Custom Chemicals Corporation
DMT-BIOTIN 95.00%
5MG
$ 500.63

Total 4 raw suppliers

Chemical Property of 1H-Thieno[3,4-d]iMidazole-4-pentanoic acid, 1-[bis(4-Methoxyphenyl)phenylMethyl]hexahydro-2-oxo-, [3aS-(3aa,4b,6aa)]-

Chemical Property:

Boiling Point:799.6±60.0 °C(Predicted)
PKA:4.74±0.10(Predicted)
Density:1.239±0.06 g/cm3(Predicted)
Solubility.:DCM, Methanol

Purity/Quality:

99% ^*data from raw suppliers

1''N-(4,4''-Dimethoxytrityl)Biotin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 1''N-(4,4''-Dimethoxytrityl) Biotin is an biotin derivative used in the novel enantioselective syntheses of (+)-Biotin.

Technology Process of 1H-Thieno[3,4-d]iMidazole-4-pentanoic acid, 1-[bis(4-Methoxyphenyl)phenylMethyl]hexahydro-2-oxo-, [3aS-(3aa,4b,6aa)]-

There total 4 articles about 1H-Thieno[3,4-d]iMidazole-4-pentanoic acid, 1-[bis(4-Methoxyphenyl)phenylMethyl]hexahydro-2-oxo-, [3aS-(3aa,4b,6aa)]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 58-85-5,22879-79-4
biotin

: 144095-63-6
N¹-4,4'-dimethoxytrityl-(+)-biotin

Guidance literature:: With dmap; In pyridine;
DOI:10.1016/0040-4039(96)00833-7

Reference yield:

: 122224-36-6
1-N-(4,4'-dimethoxytrithyl)-D(+)-biotin methyl ester

: 144095-63-6
N¹-4,4'-dimethoxytrityl-(+)-biotin

Guidance literature:: With sodium hydroxide; In methanol; for 17h;
DOI:10.1021/ol052484f

Reference yield:

: 58-85-5,22879-79-4
biotin

: 144095-63-6
N¹-4,4'-dimethoxytrityl-(+)-biotin

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂

2: pyridine; Et₃N

3: 2.33 g / aq. NaOH / methanol / 17 h

With pyridine; sodium hydroxide; thionyl chloride; triethylamine; In methanol;
DOI:10.1021/ol052484f