6-Methoxy-2-Methyl-1H-pyrrolo[2,3-b]pyridine

Base Information

• Chemical Name: 6-Methoxy-2-Methyl-1H-pyrrolo[2,3-b]pyridine
• CAS No.: 1071811-73-8
• Molecular Formula: C9H10N2O
• Molecular Weight: 162.1885
• Hs Code.: 2933990090
• Mol file: 1071811-73-8.mol

Synonyms:6-Methoxy-2-Methyl-1H-pyrrolo[2,3-b]pyridine;6-Methoxy-2-Methyl-7-azaindole

Chemical Property of 6-Methoxy-2-Methyl-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

• PSA: 37.91000
• LogP: 1.87990

Purity/Quality:

97% ^*data from raw suppliers

6-Methoxy-2-methyl-7-azaindole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 6-Methoxy-2-Methyl-1H-pyrrolo[2,3-b]pyridine

There total 1 articles about 6-Methoxy-2-Methyl-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-methoxy-2-methyl-3-methylsulfanyl-1H-pyrrolo[2,3-b]pyridine (850785-50-1) → 6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine (1071811-73-8)

Guidance literature:

With nickel; In ethanol; at 20 ℃; for 2.5h;

DOI:10.1016/j.bmcl.2008.07.103

Reference yield:

6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine (1071811-73-8) + 4-methoxy-benzoyl chloride (100-07-2) → (6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone (1071811-74-9)

Guidance literature:

6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine; With ethylmagnesium bromide; zinc(II) chloride; In dichloromethane; for 1h;

4-methoxy-benzoyl chloride; In dichloromethane; for 24h;

DOI:10.1016/j.bmcl.2008.07.103

upstream raw materials:

6-methoxy-2-methyl-3-methylsulfanyl-1H-pyrrolo[2,3-b]pyridine

Downstream raw materials:

(6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone

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