(6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone

Base Information

• Chemical Name: (6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone
• CAS No.: 1071811-74-9
• Molecular Formula: C₁₇H₁₆N₂O₃
• Molecular Weight: 296.326
• Mol file: 1071811-74-9.mol

Synonyms:(6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone

Chemical Property of (6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone

There total 1 articles about (6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine (1071811-73-8) + 4-methoxy-benzoyl chloride (100-07-2) → (6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone (1071811-74-9)

Guidance literature:

6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine; With ethylmagnesium bromide; zinc(II) chloride; In dichloromethane; for 1h;

4-methoxy-benzoyl chloride; In dichloromethane; for 24h;

DOI:10.1016/j.bmcl.2008.07.103

Reference yield:

isobutyl (2S)-2-[3-(bromomethyl)phenoxy]propanoate (1097839-43-4) + (6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone (1071811-74-9) → C25H21Cl3N2O4

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 15h;

Reference yield:

C9H8BrFO2 (1125622-45-8) + (6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine-3-yl)(4-methoxyphenyl)methanone (1071811-74-9) → C26H23FN2O5 (1125624-51-2)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2008.07.103

upstream raw materials:

6-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine

4-methoxy-benzoyl chloride

Downstream raw materials:

C₂₆H₂₃FN₂O₅

C₂₆H₂₃FN₂O₅

C₂₆H₂₃ClN₂O₅

C₂₆H₂₃ClN₂O₅