Trifluoroacetic acid o-tolyl ester

Base Information

• Chemical Name: Trifluoroacetic acid o-tolyl ester
• CAS No.: 1736-10-3
• Molecular Formula: C9H7F3O2
• Molecular Weight: 204.149
• Hs Code.: 2915900090
• Mol file: 1736-10-3.mol

Synonyms:Trifluoroacetic acid o-tolyl ester

Chemical Property of Trifluoroacetic acid o-tolyl ester

Chemical Property:

• PSA: 26.30000
• LogP: 2.46270

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Trifluoroacetic acid o-tolyl ester

There total 4 articles about Trifluoroacetic acid o-tolyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

toluene (108-88-3,15644-74-3,16713-13-6) + trifluoroacetic acid (76-05-1) → para-chlorotoluene (106-43-4) + 4-methylphenyl trifluoroacetate (1813-29-2) + 2-(trifluoroacetoxy)toluene (1736-10-3)

Guidance literature:

With lead(IV) acetate; lithium chloride; at 25 ℃; for 1h; Mechanism;

Reference yield:

ortho-cresol (95-48-7,77504-84-8) + trifluoroacetic anhydride (407-25-0) → 2-(trifluoroacetoxy)toluene (1736-10-3)

Guidance literature:

DOI:10.1021/ja01518a014

Reference yield:

lead (IV) trifluoroacetate (16656-82-9) + toluene (108-88-3,15644-74-3,16713-13-6) → 3-methylphenyl trifluoroacetate (1736-09-0) + 4-methylphenyl trifluoroacetate (1813-29-2) + 2-(trifluoroacetoxy)toluene (1736-10-3) + 3-methylphenyllead(IV)trifluoroacetate + 4-methylphenyllead(IV)trifluoroacetate + 2-methylphenyllead(IV)trifluoroacetate

Guidance literature:

In trifluoroacetic acid; at 25 ℃; Product distribution; competitive reaction in presence of benzene;

DOI:10.1021/jo01311a019

upstream raw materials:

ortho-cresol

trifluoroacetic anhydride

lead (IV) trifluoroacetate

toluene

Downstream raw materials:

benzocyclobutene

2-methylbenzotrifluoride

1-methyl-2-(trifluoromethoxy)benzene