3-Chloro-3',4'-dimethoxybenzophenone

Base Information

• Chemical Name: 3-Chloro-3',4'-dimethoxybenzophenone
• CAS No.: 116412-84-1
• Molecular Formula: C₁₅H₁₃ClO₃
• Molecular Weight: 276.719
• Hs Code.: 2914700090
• DSSTox Substance ID: DTXSID70373910
• Wikidata: Q82162304
• Mol file: 116412-84-1.mol

Synonyms:3-Chloro-3',4'-dimethoxybenzophenone;116412-84-1;(3-chlorophenyl)-(3,4-dimethoxyphenyl)methanone;DTXSID70373910;MFCD06201489;AKOS005925143;3-Chloro-3/',4/'-dimethoxybenzophenone;(3-Chloro-phenyl)-(3,4-dimethoxy-phenyl)-methanone

Chemical Property of 3-Chloro-3',4'-dimethoxybenzophenone

Chemical Property:

• Vapor Pressure: 2.91E-07mmHg at 25°C
• Melting Point: 96-98 °C
• Boiling Point: 420°C at 760 mmHg
• Flash Point: 170.1°C
• PSA: 35.53000
• Density: 1.216g/cm³
• LogP: 3.58820
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 276.0553220
• Heavy Atom Count: 19
• Complexity: 308

Purity/Quality:

98%Min ^*data from raw suppliers

3-Chloro-3',4'-dimethoxybenzophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C(=O)C2=CC(=CC=C2)Cl)OC

Technology Process of 3-Chloro-3',4'-dimethoxybenzophenone

There total 1 articles about 3-Chloro-3',4'-dimethoxybenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dimethoxybenzene (91-16-7) + m-Chlorobenzoyl chloride (618-46-2) → 3-chloro-3',4'-dimethoxydiphenylmethanone (116412-84-1)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.bmcl.2010.05.068

Reference yield:

3-chloro-3',4'-dimethoxydiphenylmethanone (116412-84-1) → 3-chloro-3',4'-dihydroxydiphenylmethanone (463355-58-0)

Guidance literature:

With boron tribromide; In dichloromethane; at -78 - 20 ℃; for 4h;

DOI:10.1016/j.bmcl.2010.05.068

Reference yield:

3-chloro-3',4'-dimethoxydiphenylmethanone (116412-84-1) → 3-chloro-3',4'-dimethoxydiphenylmethane (1239703-25-3)

Guidance literature:

With aluminum (III) chloride; lithium aluminium tetrahydride; for 2h; Reflux;

DOI:10.1016/j.bmcl.2010.05.068

upstream raw materials:

1,2-dimethoxybenzene

m-Chlorobenzoyl chloride

Downstream raw materials:

3-chloro-3',4'-dimethoxydiphenylmethane

3-chloro-3',4'-dihydroxydiphenylmethanone

Refernces