tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate
CAS No.:1016980-41-8
Molecular Formula:C18H25NO4
Molecular Weight:319.401
Hs Code.:
Mol file:1016980-41-8.mol

Synonyms:tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate;1-Boc-4-[3-(methoxycarbonyl)phenyl]piperidine

Suppliers and Price of tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 11 raw suppliers

Chemical Property of tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate

There total 4 articles about tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 744197-23-7
methyl 3-(piperidin-4-yl)benzoate

: 24424-99-5
di-tert-butyl dicarbonate

: 1016980-41-8
tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;

Reference yield: 79.0%

: 618-89-3
methyl 3-bromobenzoate

: 1-(1-(tert-butoxycarbonyl)piperidin-4-yl)-2,4,6-triphenylpyridin-1-ium tetrafluoroborate

: 1016980-41-8
tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate

Guidance literature:: With nickel(II) bromide diethylene glycol dimethyl ether; 4,4'-Dimethoxy-2,2'-bipyridin; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; In N,N-dimethyl acetamide; at 20 ℃; for 16h; Irradiation;
DOI:10.1021/acscatal.1c01416

Reference yield: 71.0%

: 2905-65-9
methyl 3-chlorobenzoate

: 180695-79-8
tert-butyl 4-bromo-1-piperidinecarboxylate

: 1016980-41-8
tert-butyl 4-(3-(methoxycarbonyl)phenyl)piperidine-1-carboxylate

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; methyl octanate; C₄₇H₆₄NO₄PPdS; sodium caprylate; sodium chloride; zinc; In water; at 45 ℃; for 36h; Inert atmosphere; Sealed tube;
DOI:10.1002/anie.201509341